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Perse were out of here.

Today's episode is one of my favorites of the year. Last week I published an

article in the Atlantic about the 10 greatest, coolest breakthroughs of 2022.

That is what were the most interesting and important discoveries or

inventions in the last year across any scientific domain, bioscience, clean

energy, vaccinology, nanotechnology, AI. What was APEX Mountain for humankind?

I've said before on this show that I think there is a negativity bias in news,

which results in this list being a surprise for me and for many listeners.

I think it's sneaky weird that this list is a surprise, that the most important

breakthroughs of the year typically come as a shock because the news media is

significantly more efficient at surfacing and its readers are more efficient at

sharing news that makes us afraid or outrage rather than news that makes us

curious or even hopeful. For example, I'm not sure that most people know we are

in a golden age of obesity therapies. Until very, very recently, most

reasonable doctors did not prescribe medications or pills or injectables for

weight loss, like the term weight loss pill was very rightly a pejorative.

...