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CoinDesk Podcast Network

Charles Hoskinson on Cardano’s Greatest Challenge, Why Ethereum Will Fail and His $200M Bet on American Healthcare | CoinDesk Spotlight

CoinDesk Podcast Network

CoinDesk

News, Tech News, Daily News, Business News

4.7698 Ratings

🗓️ 9 September 2025

⏱️ 62 minutes

🧾️ Download transcript

Summary

Insights into the past, present and future of the crypto industry with Charles Hoskinson. Follow the podcast ⁠⁠here⁠⁠. Input Output CEO and co-founder Charles Hoskinson sits down with CoinDesk for a wide-ranging conversation on the future of crypto and technology. He explains why he believes Ethereum is a "victim of its own success" and will not survive the next 10-15 years, and the "sleeping giant" of Bitcoin DeFi. Plus, his investments in revolutionizing the American healthcare system and bringing back extinct animals. - This content should not be construed or relied upon as investment advice. It is for entertainment and general information purposes. - Break the cycle of exploitation. Break down the barriers to truth. Break into the next generation of privacy. Break Free. Free to scroll without being monetized. Free from censorship. Freedom without fear. We deserve more when it comes to privacy. Experience the next generation of blockchain that is private and inclusive by design. Break free with Midnight, visit midnight.network/break-free - This episode was hosted by Jennifer Sanasie. “CoinDesk Spotlight” is produced by Sam Ewen, Jennifer Sanasie, Taylor Fleming and Victor Chen.

Transcript

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0:00.0

The future is going to be so crazy.

0:02.0

You've got quantum computers and, you know, massive incredible advancements in 3D printing and humanoid robotics.

0:09.0

And, you know, AGI, ASI, we're probably only 5, 10 years out for that.

0:13.0

It's coming at us pretty quickly.

0:15.0

And the thing I value more than anything else is not intelligence, but it's wisdom with all this stuff.

0:20.0

Knowing what to do and why

0:22.3

we should do it as opposed to how to do something.

0:30.9

Charles Hoskinson, welcome to Coin Desk Spotlight.

0:33.5

Love being here.

0:34.4

This is the first one we've done in person. So you are our very special inaugural in person. Yes, maybe we're going to kick off something fun. I don't know.

0:42.8

Really great to be here. Seizers is a beautiful place. They kind of kept up with the times. And Rare Evo is a crazy event. 2,500 people now. You know, Solana's here, Algrant's here. Hedera's here, obviously we're here. And it's just

0:55.5

amazing to watch it grow. It started 250 people just three years ago.

0:59.0

I want to talk more about why we're here in some of the events today,

1:18.1

but I want to start this conversation, taking it back a little bit.

1:23.6

You know, those folks who have been following you, who about you know that you really have this incredible mind and this incredible way of thinking about things and finding answers.

1:37.1

And I'm just curious, if you were to think back, like, what's the earliest memory you have of wanting to find answers?

1:43.5

Well, you know, I was always intellectually curious about how the world works.

1:47.3

I remember as a little kid, probably more three years old, four years old.

1:51.0

I was homeschooled.

1:52.3

My mother taught me Roman numerals, and I really hated the way Roman numerals work.

1:56.3

I was like, well, this makes no sense.

1:57.9

The system is bad.

...

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