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Nature Podcast

Cancer's power harnessed — lymphoma mutations supercharge T cells

Nature Podcast

[email protected]

Science, News, Technology

4.4859 Ratings

🗓️ 7 February 2024

⏱️ 38 minutes

🧾️ Download transcript

Summary

In this episode:


0:46 Borrowing tricks from cancer could help improve immunotherapy

T cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer cells — have struggled to treat solid tumours, which put up multiple defences. To overcome these, a team has taken mutations found in cancer cells that help them thrive and put them into therapeutic T cells. Their results show these powered-up cells are more efficient at targeting solid tumours, but don’t turn cancerous themselves.


Research article: Garcia et al.


11:39 Research Highlights

How researchers solved a submerged-sprinkler problem named after Richard Feynman, and what climate change is doing to high-altitude environmental records in Switzerland.


Research Highlight: The mystery of Feynman’s sprinkler is solved at last

Research Highlight: A glacier’s ‘memory’ is fading because of climate change


14:28 What might the car batteries of the future look like?

As electric cars become ever more popular around the world, manufacturers are looking to improve the batteries that power them. While conventional lithium-ion batteries have dominated the electric vehicle market for decades, researchers are developing alternatives that have better performance and safety — we run though some of these options and discuss their pros and cons.


News Feature: The new car batteries that could power the electric vehicle revolution


25:32 Briefing Chat

How a baby’s-eye view of the world helps an AI learn language, and how the recovery of sea otter populations in California slowed rates of coastal erosion.


Nature News:This AI learnt language by seeing the world through a baby’s eyes

News: How do otters protect salt marshes from erosion? Shellfishly


Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.



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Transcript

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0:00.0

Cross, the new series only on Prime Video.

0:04.0

You're going to be part of a masterpiece.

0:06.0

Evil knows his name.

0:08.0

Detective Alex Cross.

0:11.0

Where he lives.

0:13.0

It was in my house.

0:15.0

His darkest secret.

0:16.0

And when I'm done, the world will know the truth.

0:20.0

Based on characters created by James Patterson.

0:23.4

I'm not a monster.

0:24.4

I don't kill for fun.

0:25.8

Cross.

0:26.7

New series.

0:27.8

Watch now only on Prime Video.

0:30.2

Getting money from clients can feel like trying to wrestle honey from a grizzly bear.

0:34.0

That hasn't eaten in days.

0:36.2

While an amorous skunk clings to your leg. Not now skunky. But with zero online

0:40.8

invoice payments through Stripe and Go Cardless, you can give customers more ways to pay and keep your

0:44.9

cash flow flowing. Soon, rather than wrestling a grizzly bear, it feels more like you're cuddling

0:50.1

a koala bear. Oh. On a really soft sofa while watching your favourite soap.

0:55.0

I can't believe she was his mother.

0:57.0

The healthy business, search zero with an X.

...

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