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Nutrition Diva

Can resveratrol prevent bone loss? What the research really shows

Nutrition Diva

Macmillan Holdings, LLC

Nutrition, Arts, Education, Health & Fitness, Food

4.41.8K Ratings

🗓️ 13 May 2026

⏱️ 11 minutes

🧾️ Download transcript

Summary

In this episode, Monica breaks down the latest research on resveratrol and bone loss prevention. While the 2020 RESHAW study in Australia showed promising results for postmenopausal women, a more recent meta-analysis tells a different story. We separate the supplement hype from the evidence-based nutrition strategies that actually protect your skeleton as you age.


Key Takeaways:

  • The RESHAW Breakdown: Why 150 mg of resveratrol led to modest gains in hip and spine density—and why you’d need a lot of wine to replicate it.
  • 10-Year Fracture Risk: How to use the FRAX calculator to estimate your likelihood of a major fracture as part of your longevity strategy.
  • The Meta-Analysis Reality Check: Why mashing up 10 human trials suggests resveratrol might not be the "magic pill" for bone density.
  • The "Healthspan" Levers: Why protein timing, Fibermaxxing, and Vitamin K remain the gold standards for sarcopenia prevention and bone strength.

Resources:


Nutrition Diva is a Quick and Dirty Tips podcast, hosted by Monica Reinegal.

New to Nutrition Diva? Check out our special Spotify playlist for a collection of the best episodes curated by our team and Monica herself! 

We've also curated some great playlists on specific episode topics including Staying Strong as We Age, Diabetes, Weight Loss That Lasts and Gut Health! Also, find a playlist of our bone health series, Stronger Bones at Every Age


Have a question for Nutrition Diva? Email: nutrition@quickanddirtytips.com

Find Monica at wellnessworkshere.com


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Transcript

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0:00.0

When it comes to bone health, we're always on the lookout for something that can stop that slow slide towards osteoporosis.

0:08.1

And recently, resveratrol, a plant-based compound better known for heart health, is being discussed as a possible solution.

0:17.2

But does it actually move the needle or just nudge it?

0:26.2

Hello, I'm Monica Rineagle and you're listening to the Nutrition Diva podcast,

0:32.2

a show where we take a closer look at the latest nutrition news, trends, and research,

0:36.9

and answer your food and nutrition questions, such as the latest nutrition news, trends, and research, and answer your food and nutrition

0:38.7

questions, such as the one that I recently received from Sarah. She wrote, I've heard

0:45.5

resveratrol might help prevent osteoporosis. Is there good evidence for that? And are there

0:52.0

any concerns about safety? Now, you might recognize the compound

0:55.9

that Sarah's asking about. Resveratrol is an antioxidant compound found in red grapes,

1:02.7

as well as peanuts, pistachios, various berries, and dark chocolate. And it's usually mentioned

1:10.0

in connection with heart health or anti-aging. The bone

1:14.4

health angle is a little newer, and there is less research on it, but there are some interesting

1:20.2

findings to talk about. In particular, the Resveratrol for Healthy Aging in Women, or Reshaw study, results from which were published in 2020.

1:33.6

This was a two-year placebo-controlled study conducted in Australia and involved 125 post-manipausal women.

1:40.8

So this is the key demographic for osteoporosis prevention. And half of the women took

1:46.7

150 milligrams a day of resveratrol, and the other half took a placebo. Now, at this point,

1:55.5

because I've trained you so well, you might be wondering whether you would have to take a supplement. Could you just

2:02.9

eat more grapes and pistachios? And the answer is no. Unfortunately, this isn't a situation

2:09.9

where you could get a similar amount from foods. 150 milligrams of resveratrol is far, far more than you could ever get from food sources.

2:22.1

You'd have to drink about 11 gallons of wine or grape juice per day to equal the amount used

2:29.3

in this study. Not recommended. But back to the study. After the first year, the women taking the

...

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