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Science Friday

Can GLP-1 drugs treat addiction?

Science Friday

Science Friday and WNYC Studios

Natural Sciences, Wnyc, Science, Friday, Life Sciences

4.46.3K Ratings

🗓️ 9 April 2026

⏱️ 19 minutes

🧾️ Download transcript

Summary

Researchers are investigating whether GLP-1 drugs could be used to treat addiction disorders, following patient reports of reduced cravings.

Transcript

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0:00.0

Hi, I'm Flor Lictman, and you're listening to Science Friday.

0:06.9

GLP-1s, OZempec, Wagovi, Zepbound, you know what I'm talking about, are prescribed for weight

0:12.4

loss, diabetes, blood sugar management. But as more people take them, patients are reporting

0:17.6

an off-label use. We got a call from one of our listeners, Brian, from Wisconsin.

0:23.4

About a year ago, he decided to get on a GLP1 to manage his diabetes.

0:28.2

But he thought, you know, if I'm doing this, maybe I try to go all the way and fully reset to a healthier lifestyle.

0:35.6

And I just decided to change everything at that point in my life.

0:41.5

So that included cutting out alcohol, which I've had a long, complicated relationship with

0:48.8

over the years.

0:51.3

Typical rural Wisconsin-type drinking since I was 12, you know, beers here and there

0:59.1

with buddies all throughout high school. I suffered from a lot of depression, anxiety, and you're

1:07.6

in Wisconsin, and you're in a college town, and the drinking culture is huge.

1:12.8

So it was pretty easy to self-medicate.

1:17.2

In the years since, Brian tried not to drink so much, but it was hard to get alcohol off his mind.

1:24.0

You still plan everything around when you're going to be able to drink.

1:30.4

Are you going to have enough to drink?

1:33.0

Are you going to have to stop at this place first before you go home?

1:38.0

You know, all the little things you do that you don't realize.

1:41.9

And I thought if I was going to try to do something positive for my health

1:46.8

around the time when I was diagnosed with diabetes,

1:50.4

then why not just quit drinking also?

1:55.4

And it was strange because really the cravings for drinking seemed to really vanish.

...

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