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This Week in Startups

Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283

This Week in Startups

Jason Calacanis

Technology

4.21.4K Ratings

🗓️ 1 May 2026

⏱️ 70 minutes

🧾️ Download transcript

Summary

This Week In Startups is made possible by:

Pilot - https://pilot.com/twist

Shopify - https://shopify.com/twist

Grasshopper Bank - https://grasshopper.bank/twist


Today’s show:

An AI agent named Valerie is running a real vending machine in San Francisco — setting prices, ordering inventory, managing a bank account, and posting to Instagram. And it's not just a stunt. We’re getting an early look at the future of one-agent companies. There’s still work to do to help agents ease into the economy, potentially opening up new startup opportunities.

Jason Calacanis and Alex Wilhelm cover a stacked docket: Christian van der Henst demos the Valerie AI vending machine powered by OpenClaw; Robert Myers, CEO of Manifold Labs, breaks down Targon, a confidential GPU compute marketplace running on Bittensor Subnet 4; Jason calls Bitcoin "played out;" Alex is impressed by Anthropic's stunning $900 billion upcoming valuation; and the guys discuss Big Tech's accelerating CapEx spend, Chinese AI models in Congress crosshairs, and the NBA Playoffs.

Timestamps:

0:00 Intro & sponsor reads (Pilot, Shopify, Grasshopper Bank)

1:06 Christian van der Henst: Valerie the AI vending machine demo


4:28 Legal structure: Giving an AI agent business ownership via trust

7:23 Where agents can and can't operate today

10:10 Grasshopper Bank: Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account.

11:48 AI café in Stockholm running on agents

18:21 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off!

19:05 Robert Myers, Manifold Labs: Targon & Bittensor Subnet 4 interview

20:21 What is Bittensor? An "incubator with 128 subnets"

21:08 Shopify: Turn those What If's into sales with the ecommerce platform powering millions of businesses. Sign up for your $1-per-month trial today at https://shopify.com/twist

25:21 Pricing, utilization caps, and why GPUs are sold out

26:38 Who's using Targon? Customers, use cases, and the mom-and-pop data center argument

30:06 Pilot: Focus on your product, let Pilot handle your bookkeeping. Pilot provides the most reliable accounting, CFO, and tax services for startups and small businesses. Head to https://pilot.com/twist and get $1,200 off your first year.

35:07 Jason explains the annotated.com vision — 15 years in the making

39:11 Polymarket: Will Anthropic flip Bitcoin by Dec 31?

40:29 Jason's Bitcoin bear case: "It's played out. No incremental buyers."

46:05 MicroStrategy / Strategy updates

52:37 AI compute demand vs. the fiber overbuild analogy

55:55 Congress pressuring startups over Chinese AI models (DeepSeek, Moonshot)

57:11 A16z on the geopolitical risk of Chinese AI models

1:00:08 Reflection AI — America's open source AI champion (or lack thereof)

1:01:26 Off Duty: Knicks blow out Atlanta Hawks 140–89, Jason goes road-tripping

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Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

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Transcript

Click on a timestamp to play from that location

0:00.0

What if we give agents ownership of a company? I don't think this is legal. We actually wanted to

0:04.8

have a business fully run by an agent, having the business registered to the agents, access to the bank

0:11.7

accounts. But it also hired apparently one of the people who works in the cafe. I think the next

0:16.5

step in that's going to be one person companies and then eventually one agent companies. You will

0:20.5

report to work and talk to an agent at some point.

0:23.6

This weekend startups is brought to you by Pilot.

0:26.5

Focus on your product.

0:27.8

Let Pilot handle your bookkeeping.

0:29.6

Pilot provides the most reliable accounting, CFO and tax services for startups and small businesses.

0:35.2

Head to pilot.com slash twist and get $1,200 off your first year.

0:40.9

Shopify.

0:41.3

Turn those what-ifs into sales with the e-commerce platform powering millions of businesses.

0:46.7

Sign up for your $1 per month trial today at Shopify.com slash twist.

0:52.2

And Grasshopper Bank.

0:53.8

Time is money. Don't waste either. Go to grasshopper. bank slash twist and grasshopper bank time is money don't waste either go to grasshopper

0:57.0

dot bank slash twist and get an exclusive five hundred dollar cash bonus just for opening an account

1:02.7

all right everybody welcome back to this week and start of so i'm your host jason calcannis he's

1:06.1

alex wilhelm we've got a full docket i'm on the road um and we'll talk about the next game at the end of the show and off duty. But let's get started. Alex, what do we have on the docket today? Yeah, we're going to start with our man, Christian van der Hinst. He built something that I think is really incredible. Now, Jason, you have told us, you know, hear a twist that you're tired of open claw in a box. You don't want to hear any more open claw in a box companies. So what I did was I went out and I found the largest open claw in a box I could find in the entire world. And I brought it to you. There you. Hello, Jason. Good to see you. I don't know. I don't know if it's the largest, but I did make it special. So how to have you?

1:46.0

Do you want to see the video?

1:47.0

Yeah, let's play it.

1:48.0

So Christian took a video for us, Jason.

1:49.0

He's going to sportscast it.

...

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