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The Breakdown

Can AI Actually Trade Crypto? | The Breakdown

The Breakdown

Blockworks

Business, Investing

4.8806 Ratings

🗓️ 21 April 2026

⏱️ 32 minutes

🧾️ Download transcript

Summary

Crypto might be the world’s best test bed for AI trading — and Virtuals Protocol is running the experiment live. Weekee Tiew, co-founder of Virtuals Protocol, joins us to explain Degen Claw, their AI Council judging system, and why agents will soon replace wallets. We unpack why pure P&L is the wrong benchmark, how the trench agent concept could reshape portfolio management, and what crypto’s role is in the future of finance. Enjoy! TIMESTAMPS: (00:00) Introduction (05:29) Nexo Ad (06:03) Interview with WeeKee (09:28) Bot Strategies and Purpose of Agentic Trading (12:16) How the “AI Council” Works (14:39) Nexo Ad (15:33) How Automation Fits into Benchmarks (19:37) Incentives (24:07) What Makes You Bullish on AI Agents and Crypto in Trading? (26:35) LLMs vs Quants (28:53) The Ultimate Bull Case FOLLOW GUEST › Weekee Tiew (Virtuals Protocol) — https://x.com/everythingempty FOLLOW THE SHOW › David — https://x.com/dcanellis › The Breakdown — https://x.com/TheBreakdownBW SPONSORS › NEXO Nexo is the premier digital wealth platform. Receive interest on your crypto, borrow against it without selling, and trade a range of assets. Now available in the U.S with 30 days of exclusive privileges. Get started at http://nexo.com/breakdown Get top market insights and the latest in crypto news. Subscribe to the Blockworks Daily Newsletter: https://blockworks.co/newsletter/ DISCLAIMER As always, remember this podcast is for informational purposes only, and any views expressed by anyone on the show are solely their opinions, not financial advice.

Transcript

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0:00.0

If we close our eyes and think really, really hard about the most useful application of AI

0:03.8

within the crypto context, then I'd bet good money that you would say one of two things.

0:08.0

A clawed mythos-type model that roams around fixing security holes and plugging attack vectors

0:12.7

across all major chains, protocols and DFI smart contracts would be cool, I guess.

0:16.7

Or perhaps some kind of autonomous AI agent that can go out into chain space and make you money

0:21.6

without all the soul-crushing mental load that comes with trying to squeeze out every ounce

0:25.2

of potential profit at all times with our squishy human brains.

0:28.4

But for that to be possible, first we need AI models that can actually trade crypto effectively.

0:32.8

So can the models that we do have right now actually buy low and sell high?

0:36.7

Well, it depends. I'm your

0:38.2

host David Canellis and this is the breakdown. Let's get to it.

0:44.5

This episode is brought to you by Nexto. Step into a new era of digital wealth. Earned interest

0:53.6

on your digital assets, borrow against them without selling and trade all in one platform. Get started at nexo.com slash breakdown. Nothing said on the breakdown is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only and any views expressed by anyone in the show are opinions, not financial advice. Host and guests may hold positions in the company's funds or projects discussed. First off, it's worth making it clear that AI trading is not some totally unprecedented

1:14.6

thing.

1:15.6

Markets have been automating decision-making in judgment for decades.

1:18.6

That began with the execution layer being automated at scale in the early 1990s.

1:22.6

Before that, many trades were typically handled via open outcry floor trading.

1:26.6

That's the classic image of stockbrokers yelling orders across the New York Stock Exchange

1:30.8

trading floor and over telephones to brokers.

1:33.0

Okay, one moment, Cable Dresner, Frankfurt.

1:35.3

Yeah, I'm going to see you.

1:37.3

I'm probably not so tall there.

...

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