Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

Thank you so much for listening today. Go check out reallife pharmacology.com.

Snag your free 31-page PDF on the top 200 drugs. It's a great review if you're practicing clinician.

Or if you're a student going through pharmacology classes,

board exams, anything like that. It's really nice resource where I highlight some of the most

important testable things as well as some of the most important clinical pearls and things that

you're going to actually see in real life. So again, 31 page PDF, free to download. No cost to you, just simply

an email. And you'll get updates when we've got new content, new podcasts available, and things

like that too. So go do that at real-life pharmacology.com. All right, so let's get into the drug

of the day today, and that is Bum metanide. The brand name of this medication is

Bumex. I can't say I see it a ton in clinical practice, but I definitely do see it from time to time.

This medication is a loop diuretic. Primary use you're going to see it used for is edema. There's maybe a couple of rare

cases where I've seen it for hypertension or something like that. But by and large, you see a

patient on a loop diuretic. You can guess most of the time that it's going to be used for edema

and running off fluid.

So how does it do that?

Being a loop diuretic, it's going to block sodium and chloride reabsorption in the ascending loop of Henley in the kidney.

Okay.

And ultimately, by blocking that reabsorption, it's going to go out through the urine.

And with that loss of water, electrolytes are going to go with it. So sodium, potassium, magnesium, all that good stuff.

So that's how the drug works.

That's how we run fluid off in a patient with CHF, for example, and how the medication is going

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