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Science Quickly

Budding Yeast Produce Cannabis Compounds

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 28 February 2019

⏱️ 3 minutes

🧾️ Download transcript

Summary

Biologists have taken the genes that produce cannabinoids in weed and plugged them into yeast, making rare and novel compounds more accessible. Christopher Intagliata reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.

0:22.7

.jp. That's Y-A-K-U-Lt.C-O.jp. When it comes to a guide for your gut, count on Yacolt.

0:33.6

This is Scientific American's 60 Second Science. I'm Christopher in Taliatta.

0:38.8

The compounds THC and CBD are known as cannabinoids, because they come from cannabis, aka

0:45.0

marijuana.

0:46.5

Now biologists have taken the genes that produce cannabinoids in weed and plugged them

0:50.6

into yeast.

0:52.0

Yeah, there's several reasons.

0:53.1

The first is cost.

0:54.1

Jay Keesling is a synthetic biologist at UC Berkeley, who has previously programmed yeast

0:59.0

to cheaply produce antimilarial drugs. He says yeast could conceivably produce cannabinoids for

1:04.3

about $400 a kilogram. That's compared to the $40,000 a kilo price tag when using synthetic

1:10.6

chemistry.

1:11.7

Other benefits exist, too.

1:13.3

There are about 100 different cannabinoids that naturally occur in cannabis,

1:18.0

but it's been really hard to do research on those because there's not much available.

1:22.6

They are produced in such minute quantities in the cannabis that you'd have to purify huge amounts of cannabis

1:28.7

just to give a small quantity of them to test.

1:31.3

Keesling says they can even make cannabinoids that don't exist in nature at all by feeding

...

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