BS 176 Seth Grant on Synapse Complexity

Brain Science with Ginger Campbell, MD: Neuroscience for Everyone

Ginger Campbell, MD

Life Sciences, Health & Fitness, Neuroscience, Medicine, Brain, Science

4.8 • 896 Ratings

🗓️ 25 September 2020

⏱️ 87 minutes

🔗️ Recording | iTunes | RSS

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Summary

This is my fifth interview with molecular biologist and neuroscientist Dr. Seth Grant from The University of Edinburgh. Dr. Grant was recently recognized for his pioneering work by the Federation of European Neuroscientists. He continues to make fundamental discoveries about the structure and function of the synapse and this month we discuss the discovery that synapse complexity and diversity is greater than expected, along with the implications of these discoveries.

Links and References:

Seth Grant: University of Edinburgh
FENS EJN Award 2020
Cizeron M, Qiu Z, Koniaris B, et al. A brainwide atlas of synapses across the mouse life span. Science. 2020;369(6501):270-275. doi:10.1126/science.aba3163
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Transcript

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0:00.0	But it turns out that all of the proteins that are in the synapses that make the synapse do everything that they do.
0:06.0	All of those proteins first evolved before the brain, before multicellular organisms, they evolved in unicellular organisms that have lived
0:17.2	on the planet for several billion years before the first multicellular animal. So this tells us then that the fundamental molecular
0:27.2	machinery of the behavior of the human brain is actually fundamental molecular
0:31.8	machinery of behavior
0:33.1	in unicellular organisms,
0:34.8	and some of those molecules
0:36.8	go all the way back to the last universal common ancestor,
0:40.5	which is about three and a half billion years ago on the planet.
0:44.0	Welcome to brain science, the podcast where we explore how discoveries in neuroscience are helping unravel the
0:54.4	mystery of how our brain makes us human. I'm your host Dr. Ginger Campbell and
1:00.0	this is episode 176.
1:03.3	If you're curious about how your brain really works,
1:07.2	this is the podcast for you.
1:10.0	Before I tell you about today's guest, Dr Seth Grant, I want to remind you that you can find
1:16.0	complete show notes and episode transcripts on my website at brainscience podcast podcast.com.
1:23.0	Brain science is produced independently by me
1:26.0	and relies on the financial support of
1:29.0	listeners like you.
1:31.0	To learn more, please visit brain science podcast.com
1:34.4	forward slash donations. Please feel free to send me feedback at
1:40.4	brain science podcast at gmail.com or post voice feedback at speakpipe
	...

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