This is the Global News Podcast from the BBC World Service.

I'm Valerie Sanderson and in the early hours of Wednesday 14 December, these are our main

stories.

US scientists have made a major breakthrough in the race to generate power from nuclear

fusion, producing more energy from the process than they put in.

Researchers say they've successfully completed a trial of a personalized vaccine designed

to prime the immune system to seek and destroy cancerous cells.

The founder of the collapsed cryptocurrency exchange FDX, Sam Backman-Freed, has indicated

he'll fight extradition from the Bahamas to the United States.

Also this podcast…

The composer known for his work on the cult's crime drama Twin Peaks, Angelo Barlementi,

has died at the age of 85.

We begin with the story that had been leaked in many newspapers and scientific journals

before the official announcement.

But on Tuesday, what's being described as a major advancement in the science of nuclear

fusion was confirmed.

Today we tell the world that America has achieved a tremendous scientific breakthrough, one that

happened because we invested in our national labs and we invested in fundamental research.

And tomorrow we'll continue to work toward a future that is powered in part by fusion

energy.

That was the US Secretary of Energy, Jennifer Granholm.

Nuclear fusion described as the holy grail of energy production works by taking pairs

...