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unPAUSED with Dr. Mary Claire Haver

Brain Fog, Memory Loss, and Alzheimer’s Risk During Menopause with Dr. Lisa Mosconi

unPAUSED with Dr. Mary Claire Haver

Mary Claire Media, LLC

Medicine, Health & Fitness, Society & Culture

4.81.2K Ratings

🗓️ 24 March 2026

⏱️ 66 minutes

🧾️ Download transcript

Summary

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Lisa Mosconi, neuroscientist and associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine, New York Presbyterian Hospital. Dr. Mosconi directs the Alzheimer's Prevention Program, including the NIH-funded Women's Brain Initiative and the Alzheimer's Prevention Clinic, and was recently named director of the $50 million Program in Women's Health, Cutting Alzheimer's Risk Through Endocrinology. She is also the author of the bestselling book The Menopause Brain. Dr. Mosconi and Dr. Haver go deeper into why brain fog, memory lapses, and cognitive changes in midlife are not just frustrating. They are biologically significant, and for some women, they may signal an inflection point for Alzheimer's risk. The conversation covers the statistics women are rarely given starting at age 45, a woman has twice the risk of Alzheimer's as a man of the same age. Women are also twice as likely to be diagnosed with anxiety or depression, three times more likely to develop an autoimmune disorder affecting the brain, four times more likely to suffer from migraines, and more likely to be killed by a stroke after menopause. Guest links: Lisa Mosconi Lisa Mosconi (Instagram) Lisa Mosconi (Facebook)Lisa Mosconi Bio (LEAP)Books: “The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Confidence,” by Lisa Mosconi “The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease,” by Lisa Mosconi “Brain Food: The Surprising Science of Eating for Cognitive Power,” by Lisa Mosconi “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Transcript

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0:00.0

So, sadly, almost two-thirds of all Alzheimer's patients are women.

0:06.1

And for a really, really long time, the notion was that women live longer than men,

0:12.4

and Alzheimer's is a disease of old age.

0:15.4

Therefore, at the end of today, more women than men end up with Alzheimer's.

0:20.0

That was actually the pushback that I, the first one on my list of pushbacks that I got when I was a PhD student

0:26.3

because I wanted to look at sex differences in Alzheimer's and people were telling me it's a waste of your time

0:31.8

because it's just aging, it's just longevity, it's just that women live longer than men.

0:47.0

Thank you. It's just longevity. It's just that women live longer than men. The views and opinions expressed on unpaused are those of the talent and guests alone

0:51.8

and are provided for informational and entertainment purposes

0:54.9

only. No part of this podcast or any related materials are intended to be a substitute for

1:00.9

professional medical advice, diagnosis, or treatment. In our last episode of Unpaused, Dr. Lisa

1:07.9

Musconi helped us name something women had felt for decades but were rarely believed.

1:12.9

Menopause doesn't just change your body. It changes your brain. And Dr. Mosconi didn't bring

1:19.2

opinions. She brought scans. She brought data. She brought a scientific explanation for that

1:26.1

moment so many women described with one sentence.

1:29.1

I just don't feel it myself.

1:32.0

In this episode, we go deeper into the why.

1:36.3

Dr. Mosconi, the author of The Menopause Brain and a neuroscientist and leading researcher

1:42.5

in the Menopause Alzheimer's connection,

1:45.2

shares what we now understand about the biology of Alzheimer's,

1:49.3

including the long silent phase that can begin in midlife

1:53.4

and the real reasons women develop this disease more than men.

...

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