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Hello and welcome to the intelligence from The Economist. In London, I'm Jason Palmer.

And in New York, I'm John Fastman.

Every weekday, we provide a fresh perspective on the events shaping your world.

Akes and pains afflict us all at one time or another.

For some, it's a lifelong curse.

The available remedies do work, but the most effective come with the most risks.

We examine the pipeline of new drugs aiming to dull pain without creating different problems.

And of all the weird sentences made possible by the internet, the following may be one of the

strangest. Every October, bears in a national park in southern Alaska

compete online to see who's gained the most weight.

Ladies and gentlemen, welcome to Fat Bear Week.

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