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Science Friday

Biologists Call For A Halt To ‘Mirror Life’ Research

Science Friday

Science Friday and WNYC Studios

Life Sciences, Wnyc, Science, Earth Sciences, Natural Sciences, Friday

4.55.5K Ratings

🗓️ 8 January 2025

⏱️ 18 minutes

🧾️ Download transcript

Summary

A “mirror organism” would have proteins and DNA shaped in a way that’s the mirror image of how they naturally appear.

Transcript

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0:00.0

Listener supported, WNYC Studios.

0:11.2

In a mirror organism, many important molecules would be in opposite-handedness of those in regular life.

0:18.7

So why is that troubling to researchers?

0:22.1

Why would you ever make a microorganism that's resistant to most of our antibiotics? That's a really bad idea. It's Wednesday,

0:27.7

January 8th, and this is Science Friday. I'm SciFry producer Charles Bergquist. In so-called mirror

0:37.1

life, proteins would be right-handed instead of left, while DNA would

0:41.6

be left-handed instead of right.

0:44.1

Recently, an international group of researchers argued that work toward creating that kind

0:48.0

of organism should stop.

0:49.5

Just don't do it.

0:51.4

Synthetic biology researcher Drew Endy spoke with Ira about the concept of mirror life

0:55.5

and some of the concerns in the research community. Here's Ira. Dr. Drew Endy is one of the authors

1:02.0

of that warning. He's also an associate professor of bioengineering at Stanford University. Welcome to

1:08.0

Science Friday. Glad to be here, Ira. Thanks for having me.

1:11.3

Nice to have you. First of all, why might a researcher want to create some kind of mirror

1:15.9

bacterium or other kind of life? It's like research in general. The motivations range from

1:22.0

it's cool. Doing something new is unbelievable. There's that element of it. And then it's also practical. Like,

1:28.5

what's it good for? There's a lot of things that can be beneficial if you can make mere molecules.

1:33.4

They have different properties that might make a medicine last longer or have different

1:39.0

better impacts, fewer side effects. So it's everything from just pure basic science and the love of

1:45.1

science to some fairly, you know, useful possibilities. Right. Well, you certainly have my

1:50.7

interest now. So I want to delve a little bit deeper into this, for example, would a mirror

...

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