Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more... : 1411
The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
4.6 • 7.4K Ratings
🗓️ 6 February 2026
⏱️ 11 minutes
🧾️ Download transcript
Summary
This episode covers:
• Longevity Influence In The Epstein Files
A new DOJ document release tied to the Epstein investigation pulled physician and longevity influencer Peter Attia into the spotlight, after reports showed he appeared in the files more than 1,800 times and CBS News pulled a planned rebroadcast of its 60 Minutes profile. Dave breaks down why this story matters beyond headlines: longevity relies heavily on trust, authority, and influence, and when those foundations are shaken it exposes how fragile centralized expertise can be. He explains how biohackers can protect themselves by diversifying information sources, understanding mechanisms instead of personalities, and building health strategies that don’t collapse when one voice disappears.
• Source: https://variety.com/2026/tv/news/cbs-news-pulls-peter-attia-60-minutes-segment-epstein-1236650930/
• Age-Reversal Gene Therapy Enters Human Trials
Life Biosciences received FDA authorization to begin the first U.S. human trial of a partial epigenetic reprogramming gene therapy in the eye, using three Yamanaka factors to restore function in damaged retinal cells. Dave explains why eyes are the ideal first testing ground, what partial reprogramming actually means, and why this marks a shift from longevity theory into real clinical testing. He also clarifies what success would and would not mean for whole-body rejuvenation, and how to separate legitimate gene-therapy advances from consumer products that only claim to affect biological age.
• Continuous Ketone Monitoring Moves Toward Reality
Wearable continuous ketone monitoring is advancing beyond finger-stick meters, with companies adapting the same model that made continuous glucose monitors mainstream. Dave explains why this is a major upgrade for metabolic flexibility, keto diets, fasting, and diabetes risk management. He breaks down how real-time ketone data can reveal patterns missed by spot checks, and why biohackers should think ahead about data ownership, integration, and how ketone signals interact with glucose, sleep, stress, and training.
• Source: https://finance.yahoo.com/news/global-market-blood-ketone-meters-140900796.html
• Injectable, Wireless Brain Implants Without Surgery
Researchers are developing nano-scale, wireless brain implants capable of crossing the blood-brain barrier without open surgery, opening the door to a new class of neural interfaces. Dave connects this research to other circuit-level interventions like sound and light stimulation, explaining the broader shift from targeting molecules to tuning brain networks. He also addresses the ethical risks, including consent, privacy, and neuro-surveillance, and why biohackers should track this space early rather than after it becomes normalized.
• Source: https://longevity.technology/unlocked/longevity-news-roundup-week-5-2026/
• Generic GLP-1 Drugs Could Reshape Global Metabolic Health
India’s Sun Pharma is preparing to launch a generic semaglutide-style injectable as patent protections expire, signaling a major price drop and access expansion for GLP-1 drugs. Dave explains why this could transform obesity, diabetes, and cardiovascular disease management worldwide, while also highlighting the risks of muscle loss and metabolic weakness if these drugs are used without proper training and nutrition. He shares how biohackers should think about stacking GLP-1s intelligently, with resistance training, protein intake, and long-term maintenance strategies.
• Source: https://longevity.technology/unlocked/longevity-news-roundup-week-5-2026/
All source links are provided for direct access to the original reporting and research.
This episode is designed for biohackers, longevity seekers, and high-performance listeners who want clear thinking in a noisy health landscape. Host Dave Asprey connects ethics, emerging science, metabolic data, neurotechnology, and drug access into practical lessons for building a resilient, adaptable health strategy that works even as trends and narratives change.
New episodes every Tuesday, Thursday, Friday, and Sunday.
Keywords: longevity influencer ethics, Peter Attia Epstein files, trust in longevity science, epigenetic reprogramming gene therapy, Yamanaka factors OSK, age reversal human trials, Life Biosciences FDA trial, continuous ketone monitoring, CKM metabolic tracking, glucose ketone wearable sensors, Abbott Libre ketone sensor, metabolic flexibility biohacking, wireless brain implants, blood brain barrier neurotech, cognitive longevity technology, GLP-1 generic semaglutide, Sun Pharma GLP-1, GLP-1 muscle loss prevention, resistance training longevity, metabolic health upgrades, biohacking
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Timestamps:
0:00 - Intro
0:18 - Story 1: Attia Epstein Controversy
1:34 - Story 2: Life Biosciences Gene Therapy Trial
2:44 - Story 3: Continuous Ketone Monitoring
3:50 - Story 4: Wireless Brain Implants
4:53 - Story 5: Generic GLP-1 Drugs
6:00 - Closing Thoughts
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Transcript
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| 0:00.0 | I'm Dave Asprey. That's Dave Spell D-A-I-V-E. And this is your 10-minute weekly upgrade on the biggest |
| 0:08.0 | stories in biohacking, longevity, and the world of health. Let's go. Is the air you're breathing |
| 0:16.9 | making you sick? Just because you don't see mold doesn't mean it isn't there. |
| 0:21.6 | My friend Jason Earl has been on a mission for over two decades to help people understand |
| 0:25.6 | the hidden role of indoor air in their health. He's one of the world's leading experts on mold and indoor air quality. |
| 0:32.6 | And he created the Got Mold Test Kit to make professional grade air testing simple and accessible. |
| 0:39.5 | It uses cutting edge air sampling tech that top inspectors trust, and it's engineered for |
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| 0:51.9 | Then you send them prepaid to one of the most prestigious |
| 0:54.6 | microbiology labs in the world. No guesswork, no paperwork, and no hidden fees. You get fast |
| 1:01.5 | results, intuitive reports, and great support. And since you keep the pump, you can retest |
| 1:06.7 | any time for less. It even comes with a lifetime warranty. Mold may be invisible, but its impact |
| 1:13.2 | isn't. This kit helps you understand your environment so you can take action for your health. Go to |
| 1:18.5 | gotmold.com and use code Dave10 to save 10% and see what's in your air, because the best |
| 1:24.3 | biohackers don't guess. They test. |
| 1:35.2 | Here's your first story of the week, and it's a moment of reckoning for the longevity world. As I'm sure you have heard over the week, a new, huge release of Epstein-related |
| 1:40.6 | DOJ records has pulled physician and longevity influencer Peter Attia into the spotlight. |
| 1:47.4 | Media reports show Attia appears in the files more than 1,800 times, prompting CBS News to pull a |
| 1:54.7 | planned rebroadcast of its 60 Minutes profile of him. |
| 1:58.3 | Atia issued a public apology, calling the language in the emails |
| 2:01.8 | embarrassing and indefensible, while stating clearly that he did not participate in Epstein's crimes |
... |
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