Beyond Adrenal Fatigue: What's Really Happening With Your Cortisol with Dr. Izabella Wentz
The Energy Blueprint Podcast
Ari Whitten
4.6 • 781 Ratings
🗓️ 20 December 2025
⏱️ 53 minutes
🧾️ Download transcript
Summary
Dr. Izabella Wentz is a renowned pharmacist focused on thyroid health. In this episode, she reveals a shocking pattern: about 90% of people with Hashimoto's have alterations in how much cortisol they release throughout the day.
They struggle with brain fog, chronic fatigue, and sleep issues—tired all day, wired at night—even when they're on thyroid medications.
She's discovered something fascinating about "adrenal fatigue" that challenges both the old naturopathic model and the skeptics.
Your adrenals aren't damaged or lazy…they're perfectly capable of producing hormones. "Adrenal fatigue" is an intelligent adaptive response where your body down-regulates cortisol production to protect itself from chronic stress, essentially saying, "This is unrealistic, we can't pump out high amounts of cortisol all the time."
After being forced to find solutions during years of severe sleep deprivation with her son, Dr. Wentz developed a 4-week protocol that has now helped thousands of people. By week two, people report their anxiety dropping from an 8 to a 2. By week four, their libido returns and they feel transformed, all without hormones, complicated testing, or bags full of supplements.
Transcript
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| 0:00.0 | So one of the things we know about hormones is that they work together in symphony, right? |
| 0:05.7 | And so there's a feedback mechanism between thyroid hormones and cortisol. |
| 0:11.2 | So when we have low levels of thyroid hormones, our cortisol is going to sort of counteract to |
| 0:18.1 | counterbalance. And so we're going to have a little bit of higher levels |
| 0:21.6 | of cortisol. |
| 0:22.6 | Hey, this is Ari. Welcome back to the Energy Blueprint podcast. With me today is Dr. Isabella |
| 0:28.4 | Wens, who is a personal friend of mine and actually one of the first guests on this podcast |
| 0:35.6 | five years ago all the way back in 2017. She's an internationally acclaimed |
| 0:41.0 | thyroid specialist and licensed pharmacists who has dedicated her career to addressing the |
| 0:45.6 | root causes of autoimmune thyroid disease after being diagnosed with it herself in 2009. |
| 0:52.8 | She's the author of three books on Hashimoto's, |
| 0:56.0 | Hashimoto's Thyroiditis Lifestyle Interventions for Finding and Treating the Root Cause, |
| 1:00.0 | Hashimoto's Food Pharmacology, and Hashimoto's Protocol, which became a number one New York Times bestseller. |
| 1:06.0 | She currently lives in Texas with her husband Michael, also a good friend of mine and their son, |
| 1:11.4 | who's very cute, Dimitri, very cute, and also a source of Isabella's sleep deprivation |
| 1:18.4 | for many years now. |
| 1:20.5 | So as she will talk about in this interview, she's also the author of the new book, The |
| 1:26.4 | Adrenal Transformation Protocol, which is the subject of today's episode. |
| 1:33.7 | So, with no further ado, enjoy the episode. |
| 1:37.6 | Awesome. |
| 1:38.2 | Well, I was curious. |
| 1:40.1 | I just looked this up because I remembered you were one of the very first guests I ever had on the podcast. |
... |
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