Barclays CEO Jes Staley is stepping down, following investigations into his relationship with convicted sex offender Jeffrey Epstein. CNBC’s Geoff Cutmore reports that UK regulators have not found evidence of Staley’s involvement or knowledge of Epstein’s crimes. CNBC’s Meg Tirrell reports that Covid-19 vaccines for kids in the U.S. are coming soon, to a pharmacy or pediatrician’s office near you, and Dr. Kavita Patel, former White House policy director and fellow at the Brookings Institution, says that vaccinations are likely to occur by Thanksgiving. World leaders kick off the 2021 United Nations Climate Change Conference in Glasgow; Diana Olick reports on the COP26 agenda. Tom Friedman, New York Times foreign affairs columnist, discusses how the global energy crisis could impact climate goals, and considers how world leaders weigh environmental impact and economic stability. Plus, American Airlines has canceled over 2,000 flights since last week, blaming staffing shortages and weather concerns. In this episode: Tom Friedman, @tomfriedman Dr. Kavita Patel, @kavitapmd Diana Olick, @DianaOlick Meg Tirrell, @megtirrell Geoff Cutmore, @GeoffCutmore Becky Quick, @BeckyQuick Andrew Ross Sorkin, @andrewrsorkin