Alright, what is up everybody? Welcome to take three of this live AMA. We are celebrating our 100th episode dropping today. Yay!

We are super excited around here. The episode is with Kai Fouli and we wanted to do something a little bit special.

One, to thank you guys for being such an extraordinary community that we've been able to serve you with this many episodes.

I can't believe it. When you think about the fact that we only do 50 of these a year, the fact that we've done two years where the episodes is really pretty extraordinary.

I'm super excited about it. Can I thank you guys enough and can I thank this team enough for killing it and putting together what I think is the best in class show and I'm honored to be a part of it.

Alright, first question. By the way, Chase is going to be going to the feed so ask your questions. He's going to pull out the most impactful. The ones that hopefully will impact the most people.

So here we go. First, one up is from Selinya Ramanan.

As of late or of late, I've been grappling with the ideas of work ethic, mental health, life satisfaction and success.

In particular, Gary Vee talks about never having taken a day off for 11 years. Susanne Evans says that burnout is a myth, etc.

On the other hand, Ariana Huffington and others talk about the need for self-care and how it enhances productivity.

What does your take on all this advice? Do you personally schedule time off and do you think the amount of self-care a person needs is personally dependent?

How do you stay motivated when you are so busy that your emotional needs are compromised?

Okay, so one, let's address the individual variability, which I think is absolutely massive.

I think that all of us are wildly individual and I would not have answered that question the same way three years ago

before Lisa went through her massive microbiome disruption and as it began to really learn about the microbiome

and just how different it is from person to person and seeing the massive catastrophic impact of one food on Lisa

where I could eat it with absolute impunity. I began to realize, whoa, there really is a lot more to

individuality even at that level than we think about. And then when you think if we're that radically different at the

literal micro level, then when you accumulate all the differences, the way that we grew up, our genetic predispositions, all of that,

then you get pretty massive big differences. Now, having said that, the one thing that I think is universal is we all have

an extraordinary ability to adapt. So, and that really is my message that you can become whatever you want

and there are limits to that for sure. I don't think that we're completely blank canvases. I just

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