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Nature Podcast

Audio long-read: How COVID exposed flaws in evidence-based medicine

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 28 June 2021

⏱️ 24 minutes

🧾️ Download transcript

Summary

A deluge of trials has stress-tested the systems that produce evidence.


Around the world, researchers have raced to test therapies to treat COVID-19. The speed and urgency of this task has revealed both the weaknesses in the collection and use of research-based evidence, and how well-run trials have helped save lives.


This is an audio version of our feature: How COVID broke the evidence pipeline


Hosted on Acast. See acast.com/privacy for more information.

Transcript

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1:04.8

Welcome to this audio long read from nature.

1:08.0

In this episode, How COVID Broke the broke the evidence pipeline, written by Helen Pearson

1:13.1

and read by me, Benjamin Thompson. It wasn't long into the pandemic before Simon Carly realized

1:24.1

we have an evidence problem. It was early 2020 and COVID-19 infections were starting

1:31.1

to lap at the shores of the United Kingdom, where Carly is an emergency medicine doctor

1:35.9

at hospitals in Manchester. Carly is also a specialist in evidence-based medicine, the

1:43.0

transformative idea that physicians should decide

1:45.9

how to treat people by referring to rigorous evidence, such as clinical trials. As cases of COVID-19

1:53.9

climbed in February, Carly thought that clinicians were suddenly abandoning evidence and reaching

1:59.4

for drugs just because they sounded biologically

2:01.8

plausible. Early studies Carly saw being published often lacked control groups or enrolled too

...

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