Apr 04 2025 This Week in Cardiology

This Week in Cardiology

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Cardiology, Science, Medicalpractice, Electrophysiologist, Medscape, Internalmedicine, Medicaldecisionmaking, Expertcommentary, Eartrhythmdisorder, Health, Perspective, Medicine, Healthnews, Medicalexpert, Endoflifecare, Clinicaltrials, Health & Fitness

4.9 • 876 Ratings

🗓️ 4 April 2025

⏱️ 27 minutes

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Summary

Trials from the 2025 American College of Cardiology scientific sessions, including the WARRIOR, PROTECT TAVI, DAPATAVI, and SOUL are reviewed by John Mandrola, MD

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I Thank you Comments

II WARRIOR Women’s IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

Keep Fighting INOCA After Neutral WARRIOR Trial https://www.medscape.com/viewarticle/keep-fighting-inoca-after-neutral-warrior-trial-2025a10007uf

III Cerebral Embolic Protection in TAVI

PROTECT TAVI https://www.nejm.org/doi/full/10.1056/NEJMoa2415120
PROTECTED TAVR https://www.nejm.org/doi/full/10.1056/NEJMoa2204961
Instrumental Variables in Randomized Trials https://evidence.nejm.org/doi/10.1056/EVIDctw2400204

IV DAPATAVI

SGLT2 Inhibitors Progressing to New Standard After TAVI https://www.medscape.com/viewarticle/sglt2-inhibitors-progressing-new-standard-after-tavi-2025a100081y

Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation https://www.nejm.org/doi/full/10.1056/NEJMoa2500366

V SOUL Study of Oral Semaglutide and CV outcomes in Diabetes

Oral GLP-1 Receptor Agonist Reduces CV Risk https://www.medscape.com/viewarticle/oral-glp-1-receptor-antagonist-reduces-cv-risk-2025a10007kr

Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2501006

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The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

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Transcript

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0:00.0	You're listening to This Week in Cardiology from the heart.org, Medscape Cardiology.
0:05.7	This podcast is intended for health care professionals only.
0:08.8	Any views expressed are the presenters' own and do not necessarily reflect the views of WebMD or Medscape.
0:15.0	Hi, everyone.
0:16.3	This is John Mandrola from the heart.org medscape cardiology, and this is this week in cardiology for April 4th,
0:23.2	2025. This week, ACC and Era Reviews, including the Warrior trial, Protect Tavi, Dapitavi, and the
0:33.7	Soul Trial. First up, some comments. As I said last week, I would be at the European
0:40.8	heart rhythm meeting instead of ACC. The European heart rhythm is a great meeting. I had to give
0:46.1	a debate against PFA, against one of the most experienced PFA doctors in the world, Dr. Borer-Schmidt
0:52.2	from Frankfurt. The trouble is I had to admit to the audience that I was now a PFA doctors in the world, Dr. Boris Schmidt from Frankfurt. The trouble is I had to admit to the
0:56.0	audience that I was now a PFA convert. I haven't actually done a thermal evaluation in nine months.
1:03.8	So what I did instead during the debate is to pretend that I was a neutral Martian and I tried
1:08.7	to give an unbiased review of the actual evidence,
1:11.7	which is decent for PFA, but far from definitive.
1:16.2	Now, more on PFA next week, because there was a big trial of PFA versus Crio Balloon presented
1:21.5	at ERA.
1:22.8	Now I want to express my thanks to the many people who came up and said they listened to the
1:27.2	podcast.
1:28.0	Gosh, there were so many countries' representative, too numerous to even list. It means so much to me
1:33.5	that when you say hello, another great thing happened at era, a organizer set up a 5K, and thanks to
1:40.6	the era president, Dr. Helmut Purefurner, for running with me, but sorry for slowing you down, Helmut.
1:47.4	Finally, I was happy to speak in a session at Era on Critical Appraisal.
	...

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