Anti-Aging with Rapamycin Over 50: Extending Healthspan w/ Alan Green, MD

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Fasting, Nutrition, Autophagy, Ketogenic, Keto, Health & Fitness, Ketodiet, Medicine

4.8 • 1.2K Ratings

🗓️ 2 April 2023

⏱️ 65 minutes

🔗️ Recording | iTunes | RSS

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Summary

Alan Green, MD has been using low-dose rapamycin in his clinical practice for years. We discuss the many potential health benefits and ways this compound can be used as a tool to support healthspan and prevent age-associated diseases.

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Show Notes:

05:05 Rapamycin stops this deterioration and the development of dementia.
09:47 Pharmaceuticals do not treat end-stage disease.
11:15 Rapamycin is anti-mTOR. mTOR is involved in all age-related diseases.
19:35 Evolution’s way to promote new gene variations is to eliminate those with old variations with a short lifespan.
24:40 Ageing is a programed genetic timebomb.
30:50 Slowing mTOR with rapamycin slows ageing.
37:40 Transplant patients do not get the age/health benefits because the dosing of rapamycin is too high.
40:18 Once a week dosing gives a high level at the beginning of the week to knock out mTOR1 and it was low enough at the end of the week to not interfere with mTOR2.
41:15 Reducing mTOR1 reduces the activity of the innate immune system.
42:45 Decreasing the innate immune system is good for stopping chronic inflammation and age-related diseases.
48:30 A typical dose is 6 mg. It is less for a smaller healthy person.
50:17 Rapamycin is good for sports performance because it is good for cardiac performance.
54:10 Rapamycin helps maintain strength and quality of muscles.
55:30 Bodybuilders do not benefit from rapamycin.

Transcript

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0:00.0	Rappamysen is very good for sports performance because it's very good for age associated to
0:09.8	crime and quiet function. In other words, you see runners after sort of like 30, or like if you're
0:20.9	looking at Olympic runners, they're having a progressive decline from like world records like just
0:26.8	about two hours, two weeks, three hours, two weeks, six hours. This is characteristic of like
0:34.5	everything with a heart. Animal animals with a heart have it age associated to crime in
0:41.8	heart function. Rappamysen is real good for that. That's sort of like the studies that like
0:47.2	that cable and steal your dogs. He was showing their healthy older dogs. Rappamysen wasn't
0:53.1	proving to have heart function and it could show that the echocardiogram. They're on mice that
1:00.5	could show exactly how it was happening. It was related to a change in crime like fuel. It's like
1:11.2	there was a shift in what the mitochondria was burning. They were burning like all the people
1:17.3	look very fuel and younger people, they were burning more like the high octane fuel and Rappamysen
1:23.8	was sort of like shifting that back to sort of like the kind of highway fuel they were burning
1:29.4	and younger people and like they map the entire protein picture and they could see that the
1:36.2	proteins involved in mitochondria were the things that were changing. People who are sort of like
1:41.3	very attuned to that like cyclists, which we notice that on Rappamysen all of a sudden
1:49.6	they're better cardiac performance. They can cycle faster. They're maximum heart rate is better
1:55.9	they're cycling serious better. So improve athletic performance.
2:10.0	Hey guys welcome back. So today's show with Alan Green is brought to you by myoscience nutrition.
2:13.6	As you can tell we're talking a lot about aging and natural ways to help to optimize your body's
2:17.8	aging response. A natural product that you may want to consider when it comes to supporting
2:21.7	metabolic health as you age is burbring fasting accelerator. A lot of people don't really
2:26.0	recognize the power of burbring. It's one of the most effective natural products to help support
	...

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