An aggressive cancer’s loophole, and a massive field of hydrogen beneath the ocean floor

Science Magazine Podcast

Science Podcast

News Commentary, News, Science

4.2 • 791 Ratings

🗓️ 11 September 2025

⏱️ 35 minutes

🔗️ Recording | iTunes | RSS

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Summary

First up on the podcast, aggressive tumors have a secret cache of DNA that may help them beat current drug treatments. Freelance journalist Elie Dolgin joins host Sarah Crespi to talk about targeting so-called extrachromosomal DNA—little gene-bearing loops of DNA—that help difficult-to-treat cancers break the laws of inheritance. Next on the show, producer Meagan Cantwell talks with Weidong Sun, director of the Center of Deep Sea Research at the Chinese Academy of Sciences, about the discovery of a hydrogen-rich system so large it makes up at least 5% of current estimates for global hydrogen emissions from abiotic sources. They discuss how hydrogen gas rising from the mantle reacting with oxygen could have triggered an explosion that formed holes hundreds of meters across and dozens of meters deep. This week’s episode was produced with help from Podigy. Authors: Sarah Crespi; Elie Dolgin; Meagan Cantwell Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	This podcast is supported by the Icon School of Medicine at Mount Sinai, the academic arm of the Mount Sinai Health System in New York City, and one of America's leading research medical schools.
0:11.1	What are researchers on heart health working on to transform patient care and prolong lives?
0:16.6	Find out in a special supplement to Science magazine prepared by the Icon School of Medicine
0:21.4	at Mount Sinai in partnership with science. Visit our website at www.combe.combe
0:26.3	science.org and search for Frontiers of Medical Research, dash heart. The icon school
0:32.7	of medicine in Mount Sinai, we find a way. This podcast is supported by Jian Zhao Tong, Liverpool University,
0:39.4	where East meets West to redefine the future of learning and discovery. We're turning 20 in
0:45.6	26. Celebrate with us as we honor two decades of breakthroughs, cross-cultural exchange, and
0:52.3	world-changing research. Curious about how we're making waves, join the party at www.xjtl.org.org.
1:00.5	org.org.
1:01.3	dot edu.
1:01.8	CN. slash E.N.
1:05.3	This is a science podcast for September 11th, 2025.
1:09.5	I'm Sarah Crespi.
1:10.8	First this week, cancer biologists are
1:13.2	digging into a secret cache of DNA that helps difficult to treat cancers break the laws of
1:19.1	inheritance. Freelance journalist Ailey Dolgan talks about targeting these extra-chromosomal
1:24.7	DNA loops and their role in aggressive cancers.
1:29.1	Next on the show, producer Megan Cantwell talks with Wei Dengsun about the discovery
1:33.7	of an undersea hydrogen-rich system so enormous that it makes up at least 5% of current estimates
1:41.5	for global hydrogen emissions from abiotic sources.
1:45.7	They also talk about some of the explosions it may have triggered.
	...

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