Dr. Archina Sadu is our guest.

She's an endocrinologist board certified.

That means hormones.

And she specializes in diabetes.

She is the director of the system diabetes program at Houston Methodist.

And we're talking about OZMPIC, something that keeps coming up in conversation after conversation.

As I talk to people who you compliment, you look great.

You've lost weight, and they say,

O-Zimpe, or some variation of that drug class.

Dr. Sado, I want to go back to, you gave three items.

Number three was appetite suppression.

Number two was raising the ability of the pancreas to secrete insulin.

The first was, as I understood it, delaying the food vacating in your stomach.

Does that mean it's holding the food longer in your stomach so that you fill full and you don't have a need to refill that?

I want to make sure I understand that.

Exactly, yeah. So it is delaying the emptying process of the stomach.

And so the gastric contents, whatever you've eaten, are sitting in the stomach a little bit longer.

The stomach wall is stretched out a little bit more.

And so that in and itself signals your brain to stop eating as much

because obviously you don't want to, normally you don't want to overeat the stomach volume. So

it's called delayed gastric emptying. It's a well-known effect of the drug that we actually desire

because, one, it makes you eat less.

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