Hello and welcome to NewsHour from the BBC World Service. We're coming to you live from London.

My name's Paul Henley. Coming up on the program, promising results from an early clinical trial

targeting dormant cancer cells in breast cancer survivors who are at higher risk of the disease

returning.

These drugs were highly effective. We were able to eliminate the cells in approximately 80% of the patients who we treated. And most importantly, in the patients who cleared the cells,

we did not see recurrences now up to seven years from the time they were

treated. More on that in about 40 minutes time. But first, work is continuing in the east of Afghanistan

to rescue thousands of people still caught up in the aftermath of Sunday's earthquake. The Taliban

government says more than 1,400 people have been killed.

The UN says hundreds of thousands have been affected,

and that mountainous roads blocked by landslides and rockfalls

have been the biggest challenge for response teams.

Helicopters are trying to reach affected areas.

The earthquake struck the remote Kuna province.

Salam al-Janabe is from the children's charity UNICEF and is currently in the capital Kabul.

We are 24 hours past the first night of so many people. We hear that around 600 and more homes have

been lost have spent out in the cold night.

So our next priority now is shelter. So UNICEF sending out tarpaulin, tents, kits where you have

kitchens, people have lost everything. Our correspondent, Jogita Limei, has been to Jalalabad, the nearest major city to the epicentre of the earthquake,

where efforts are continuing to treat those injured.

We're at the airbase in Jalalabad, which is the closest airport to the worst affected areas of the earthquake.

And the reason we've come here is because we actually tried to get to the worst affected areas earlier,

...