Acute Severe Hypertension - part 3
Hospital and Internal Medicine Podcast
Gil Porat, M.D., FACP, CPT
4.8 • 587 Ratings
🗓️ 27 April 2020
⏱️ 15 minutes
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| 0:00.0 | Before I get too deep onto some of the new topics, I want to cover my tracks a little bit on some |
| 0:06.4 | of the topics I already covered. One was Labelol. And I believe in the last lecture I was saying |
| 0:13.0 | that the beta blocker ratio to alpha blocker ratio in intravenous libeta-law is 7 to 1. So basically, intravenous labatalol is 7 to 1. So basically intravenous libadol pretty much is a beta |
| 0:25.0 | blocker with a little bit of alpha blocking activity. What I didn't point out of that time is that |
| 0:31.5 | oral labatalol is actually a bit of a different drug than intravenous libad-l. So oral labetol, the beta-blocker to |
| 0:41.0 | alpha-blocking ratio is 3 to 1. So oral labetol is really more of a combination drug with still a higher |
| 0:49.6 | degree of beta-blockade to alpha-blocking, but not nearly as much of a degree as intravenous labato |
| 0:57.4 | all that is 7 to 1 ratio. The other thing that I wanted to remember to mention is when I was talking |
| 1:04.0 | about the etiologies of very high blood pressures, I said one of the main ideologies, the number |
| 1:10.4 | one reason, is noncompliance with |
| 1:13.0 | blood pressure lowering medication. So we've all met the patient who has a superpower of making |
| 1:17.6 | cigarettes disappear but can't afford the $4 a month blood pressure lowering medication. That's generic. |
| 1:24.8 | And then I went into a whole bunch of other ideologies of very high blood pressures, |
| 1:29.2 | but one I forgot to mention, and I think is very important, particularly for people who take care |
| 1:35.2 | of people in hospital settings and intensive care units, and any hospital floor for that matter, |
| 1:42.2 | is hospital fluid overload. I atrogenic fluid overload. So I don't want to |
| 1:48.0 | blame just patients for high blood pressure. A lot of times it can be because we give too much IV fluid. |
| 1:56.2 | Leaders and liters of salty fluid will cause the systolic and diastolic pressure to go up, and the way |
| 2:02.8 | to treat that form of hypertension from fluid overload is fluid removal. Often treating volume |
| 2:10.7 | overload with other anti-hypertensives will yield very unsatisfying results. The last thing I want to cover my tracks a little bit on is this term |
| 2:21.3 | hypertensive urgency because I know it does drive some of you crazy. |
| 2:25.6 | So Hannibal Lecter would tell you if people make you sick, |
... |
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