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Science Friday

A virus hunter in Nigeria has thoughts on the Ebola outbreak

Science Friday

Science Friday and WNYC Studios

Natural Sciences, Wnyc, Science, Friday, Life Sciences

4.46.3K Ratings

🗓️ 5 June 2026

⏱️ 20 minutes

🧾️ Download transcript

Summary

A Nigeria-based molecular biologist breaks down the current Ebola outbreak, and what's needed to improve disease monitoring across Africa.

Transcript

Click on a timestamp to play from that location

0:00.0

Hey, it's Flora and you're listening to Science Friday.

0:06.1

The current Ebola outbreak in the Democratic Republic of the Congo and neighboring Uganda is caused by the Bundy-Busia virus.

0:13.7

There's no specific treatment or vaccine for this strain, unlike the more common Zaire strain, which caused the 2014 outbreak.

0:21.7

Here to give us an update and put the news in context is Dr. Christian Happy.

0:26.3

He's a molecular biologist who has dedicated his career to improving genomic sequencing

0:31.4

capabilities and virus monitoring across the continent of Africa.

0:35.9

Dr. Happy is a distinguished professor at Redeemer's University and

0:39.0

runs the Institute of Genomics and Global Health in Nigeria. Welcome to Science Friday. Thank you for being here.

0:45.8

Thank you. So I want to start with the, I want to start with the Bundy-Bujo virus. What's different about it compared to this Zayr strain?

0:57.0

The Bundy-Bujo virus or strain of Ebola is different from the Zaire strain, simply because

1:05.7

it has diverged. It has evolved. It has followed a different evolutionary path. And for that reason,

1:14.1

the virus is quite divergent from those are your strain. And that divergence actually creates

1:20.0

its own challenge because diagnostics, vaccines, and drugs are often very strain-specific

1:26.8

because they are targeting some very specific

1:29.6

epitops in any virus. And because of the Bungibuja virus has not been studied extensively,

1:36.9

that is a reason why now we want to use this outbreak in order to not only sequence a virus,

1:43.4

but actually leverage the data that will be coming

1:45.6

from the outbreak to develop the necessary countermeasures. And these countermeasures are drugs,

1:51.1

vaccines, and diagnostics. Had it not been sequenced before?

1:56.1

Not really. I think, you know, when we had that last outbreak, when the Bujim-Bujan outbreak,

2:03.8

I mean, occurred, I think that was probably 2007.

2:10.6

There were, I mean, at that time, genomic sequencing was not really at the stage where it is now.

...

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