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slash setup welcome welcome to cool stuff ride home mark this path joined by

reggie Rizu on today today's episode, one macro analysis suggests

exercise or physical activity may be the best treatment for depression. We'll explain. And on

this day in history, the macadamia nut crop starts in Hawaii. That's coming up on cool stuff.

Well, after conducting a large meta-analysis, comparing effects of selective serotonin re-uptake inhibitors, more commonly known as SSRIs, with various forms of exercise, a team of researchers determined that nearly all common forms of physical activity display a greater potential for improving symptoms of depression

than the flagship antidepressant medication. That per report from Andy Corbly and the World

at Large publication. Now, physical activity is defined in a variety of ways, including dancing,

yoga, running, walking, jogging, cycling, mixed aerobic exercise, weight training, and

Tai Chi. And while the risk of bias was determined to be high in many of the component analysis,

the study published in the British Medical Journal contained a number of interesting findings

that anyone struggling with depression should at least be aware of and

consider. The history of SSRIs is fascinating in its own right. In 1998, the psychiatric medication

fluoxetine, better known by its brand name Prozac, was introduced in the U.S. Five other drugs

followed in subsequent years, and by 2004, total Medicaid spending on SSRIs

and a similar class of drugs called SNRIs had grown to $2 billion annually.

Now, like many pharmaceutical products, skepticism and criticism followed, though SSRIs continued

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