meta_pixel
Tapesearch Logo
Log in
Sidedoor

A Mold with a Grudge

Sidedoor

Smithsonian Institution

African American History And Culture, American History, Exhibits, Dc, History, Science, Sidedoor, History Of The World, Society & Culture, The Smithsonian, Washington, Natural History, Pop Culture, Smithsonian, Exhibit, Tony Cohn, Zoo, National Museum, Air And Space, National Zoo, Art19, Museum, Postal Museum

4.62.3K Ratings

🗓️ 10 December 2025

⏱️ 40 minutes

🧾️ Download transcript

Summary

It started with a messy lab and a mysterious mold. But turning “mold juice” into the world’s first antibiotic would take a sick policeman, a market cantaloupe, and an extraordinary wartime collaboration between scientists, governments, and industry. This is the story of how penicillin changed the world.

Guests:

Kevin Brown, Trust Archivist to Imperial College Healthcare NHS Trust and curator of the Alexander Fleming Laboratory Museum at St. Mary’s Hospital; author of Penicillin Man: Alexander Fleming and the Antibiotic Revolution

Diane Wendt, curator in the Division of Medicine and Science at the Smithsonian's National Museum of American History

Transcript

Click on a timestamp to play from that location

0:00.0

This is Side Door, a podcast from the Smithsonian with support from PRX. I'm Lizzie Peabody.

0:14.3

A lot of scientists from the early 1900s were known for being quirky.

0:30.1

Albert Einstein famously did not like to wear socks.

0:34.4

Marie Curie hated public speaking so much.

0:40.2

She almost skipped her own Nobel acceptance ceremony.

0:47.0

Nicola Tesla refused to speak to women wearing pearls and would only stay in hotel rooms divisible by three.

0:51.3

And then there was this guy, Alexander Fleming.

0:59.9

This was a man who could stand and stay at you for an hour without saying a word.

1:02.0

He didn't feel uncomfortable.

1:03.2

You would.

1:12.5

This is Kevin Brown, trust archivist at St. Mary's Hospital in London and curator of the Alexander Fleming Laboratory Museum.

1:15.6

He says Fleming was a bit of an odd duck.

1:19.7

To his colleagues at St. Mary's, he was known as Flem.

1:26.4

Flem was short, wore a bowtie, and smoked three packs a day. And he had an unusual hobby.

1:29.9

He was interested in art. He didn't use oils of watercolors. He did what he called germ paintings. Fleming was a bacteriologist, so he studied

1:37.2

and taught about bacteria for a living. But bacteria often grow in bright colors, which he

1:43.4

liked to use to create artwork, germ paintings.

1:47.3

Basically painting by numbers with books.

1:50.4

And that is why, in the summer of 1928, Fleming went on vacation and left a bunch of petri dishes

1:57.1

sitting out in his lab at St. Mary's Hospital Medical School.

2:00.7

You know, just in case

2:01.9

some grew into cool colors while he was away. And when he returned, at the end of the summer,

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Smithsonian Institution, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Smithsonian Institution and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.