#84 - AMA #10: Low testosterone, hypothyroidism, building muscle (and preserving it while fasting)

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.7 • 7.3K Ratings

🗓️ 16 December 2019

⏱️ 11 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this “Ask Me Anything” (AMA) episode, Peter answers a wide range of questions from subscribers. Bob Kaplan, Peter’s head of research, asks the questions. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA.

If you’re a subscriber, you can now listen to this full episode on your private RSS feed. You can also listen to this full episode on our website at the AMA #10 show notes page.

We discuss:

Does testosterone supplementation impact longevity? [2:40];
Under what conditions does Peter decide to treat patients who have low testosterone? [8:50];
Are there risks involved with testosterone replacement therapy? [17:10];
How does Peter diagnose and treat hypothyroidism? [21:30];
How might someone do time-restricted feeding while also adding muscle mass? [26:30];
If building muscle requires higher levels of IGF-1, should we be concerned about longevity? [34:45];
How to preserve muscle mass while fasting [41:45];
Is it possible to simultaneously lose fat and add muscle mass? [46:30]; and
More.

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Transcript

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0:00.0	Hey everyone, welcome to the Peter Atia Drive. I'm your host, Peter Atia.
0:10.0	The drive is a result of my hunger for optimizing performance, health, longevity, critical thinking,
0:15.7	along with a few other obsessions along the way. I've spent the last several years working
0:19.6	with some of the most successful top performing individuals in the world, and this podcast
0:23.8	is my attempt to synthesize what I've learned along the way to help you live a higher quality
0:28.3	more fulfilling life. If you enjoy this podcast, you can find more information on today's
0:32.5	episode and other topics at peteratiamd.com.
0:41.7	Welcome to another edition of Ask Me Anything. Once again, I'm joined by my head of research
0:46.5	and my sidekick, Bob Kaplan. In this episode, we go really deep on about three things. There's
0:53.5	no speed round, but I think we make up for it by just the depth rather than the breadth. The
0:58.6	first thing we talk about is testosterone replacement for men specifically. When it's appropriate,
1:03.1	related risks benefits, the laboratory values one should and shouldn't care about. Apologies
1:08.4	that this one is a little more gender specific, but I think we've also already covered this on
1:12.7	the female side. This is a very male-centric view of testosterone replacement therapy.
1:17.7	Second thing we jump into is thyroid replacement therapy, and just in general thyroid hormones,
1:23.2	how they're produced, how the diagnosis of hypothyroidism is made in my opinion, how that
1:28.2	differs from maybe the standard way that people think about it, and all sorts of other
1:32.2	tangential things around that. And then lastly, we talk about exercise. Specifically, we talk about
1:37.3	exercise and how it relates to nutrition with respect to building muscle. Now to be completely
1:42.1	clear, and I disclose this fully in the episode, I don't consider myself an expert on muscle
1:47.1	building, body building, anything like that. You certainly wouldn't want me as your coach if you
1:51.8	were training for such things. But at the general population level, which is where I consider myself
	...

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