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Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

798: Is Your Skincare Aging You? Decoding DNA Methylation & Biological Age with Cristiana Banila

Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

Kay Durairaj, MD, FACS @beautybydrkay

Business, Arts, Fashion & Beauty, Health & Fitness, Management & Marketing, Medicine

4.9608 Ratings

🗓️ 20 January 2026

⏱️ 34 minutes

🧾️ Download transcript

Summary

In this cutting-edge episode of Beauty Bytes, I sit down with Cristiana Banila, the Chief Scientific Officer and co-founder of Mitra Bio, to discuss the revolutionary field of skin epigenetics. We explore the difference between genetics (the hardware) and epigenetics (the operating system) and how non-invasive tape stripping technology allows us to measure biological age and cellular damage without a single biopsy. Cristiana reveals fascinating data on how sun-protected skin is biologically 3.8 years younger than exposed skin, and we tackle a controversial finding from her research: why short-term retinoid use might actually accelerate biological aging by increasing inflammatory markers . We also discuss the future of skin cancer detection and why "resilience" is the new anti-aging standard.

Transcript

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0:00.0

Well, hello, hello, guys. You're listening to Beauty Bites with Dr. K.

0:19.2

Secrets of a Plastic Surgeon, and today's podcast is so interesting.

0:23.8

We are going to talk all about epigenetics, and this is so exciting because we'll be able to see molecular change and DNA structure that predicts if your chronologic age and biologic age are lining up, if you're getting older or younger from different interventions.

0:38.5

We are interviewing Christiana Banila, who is harnessing the power of epigenomics for this really precise diagnostics.

0:46.4

Christiana is CSO, chief scientific officer and co-founder of MitraBio, and this is a Kulsaventures-backed startup.

0:56.9

And this is really interesting, non-invasive skin testing, and we're looking at data modeling epigenetics, which shows how your skin is aging

1:03.8

from different interventions, different topicals. It's such exciting technology.

1:10.3

Christina graduated from Oxford and Princeton University, where she studied biochemistry and

1:14.7

public health economics, and she specialized in molecular diagnostic development.

1:19.8

She has her PhD from Queen Mary University of London, all about developing self-sampling

1:25.4

epigenetics-based testing for early cancer detection.

1:29.5

And that test that she had developed performed well in clinical trials,

1:33.2

and it's recently been implemented by the NHS cervical screening program.

1:36.7

So that's wonderful.

1:38.0

Congratulations.

1:39.3

Christina has been named Forbes 30 under 30 for Europe, Science and Healthcare in 2023.

1:44.8

Welcome to the podcast.

1:46.5

Thank you.

1:47.3

Good to be here.

1:49.0

Yeah.

1:49.4

So I'm so super excited.

1:52.4

Can you talk a little bit about, like, for the lay audience, what is epigenetics the study of and how does it influence our behaviors or vice versa?

...

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