Welcome back to the Diet Dr. Podcast. I'm your host, Dr. Brett Scher.

Today we're talking about seed oils and vegetable oils, polyunsaturated fatty acids,

linoleic acid. Pretty controversial topic. And for this, we have a bit of a treat

because this is another compilation podcast where we're going to talk to Nicola Gess, to Trocalation,

to Ethan Weiss, to Ben Bickman, to Raphael Sertory, and to Amber O'Hern. So quite a compilation

of people with different levels of expertise, different specific areas of interest, and different

opinions on sort of the conclusion of all the evidence.

So what we're going to do is we're going to walk through what does the evidence support

and how do these individuals interpret the evidence, what it means for them as individuals

and what it means for them potentially as clinicians and what they recommend to other people.

So I want to lay the

groundwork a little bit about why this is such a controversial topic. And when I was, you know,

in medical school and residency and fellowship, there was no question. Vegetable oils were healthy.

They are healthy. They lower LDL. They lower cardiovascular risk. And they are basically a health food that we should be eating more of.

Then as I started to learn more about it and hear different sides of the equation, I learned about the mechanistic data.

And the mechanistic data of regarding linoleic acid is is concerning.

I mean, the pro-oxidation, how it can change the structure of membranes,

how it could potentially induce insulin resistance, how it can deuce inflammation. And then

there's also some randomized controlled trials, so much older trials in Minnesota coronary

experiment, the Sydney Diet Heart Study, which showed a worsening of cardiovascular

and all cause mortality for those who ate higher levels of linoleic acid.

But the observational data that we have suggests that there's a benefit to eating more

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