77. How Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease, with Tucker Goodrich

Paul Saladino MD podcast

Paul Saladino, MD

Medicine, Health & Fitness

4.8 • 2.7K Ratings

🗓️ 2 November 2020

⏱️ 122 minutes

🔗️ Recording | iTunes | RSS

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Summary

Tucker Goodrich is a technology executive in the financial industry who designs, runs, and debugs complex systems in high-risk environments. Areas of expertise include risk management, systems management, and cyber-security.

After experiencing some personal health crises and realizing that the ‘solutions’ offered by medical professionals weren’t working or addressing causation he started applying the same approach in research and evaluation of data to his own health issues to determine root causes.

His interests have focused on dietary and environmental drivers of chronic disease, including carbohydrate, wheat, and various classes of fats. Specifically, he's attempting to understand and popularize understanding of the mechanisms driving the diet-derived explosion in so-called chronic diseases (or diseases of civilization). He is active on twitter (@tuckergoodrich, has a blog called Yelling Stop, is an Expert Advisor for the nutrition start-up Nutrita, and has been a guest on numerous podcasts.

Time Stamps:

Podcast Youtube

0:09:38 0:03:21 Podcast Begins

0:11:12 0:04:55 What is Linoleic Acid?

0:16:44 0:10:27 How Linoleic acid caused disease

0:21:06 0:14:49 Understanding cardiolipin and the electron transport chain

0:23:28 0:17:11 Linoleic acid drives mitochondrial dysfunction, causes chronic illness

0:26:41 0:20:24 Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026740/

0:32:56 0:26:39 Linoleic acid is uniquely damaging

0:35:30 0:29:13 Myths surrounding linoleic acid

0:38:19 0:32:02 The supremacy of animal fats

0:41:05 0:34:48 Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA https://journals.physiology.org/doi/full/10.1152/ajpheart.00480.2004?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

0:42:25 0:36:08 How seed oil consumption leads to necrosis and CVD

0:49:38 0:43:21 Mainstream understanding of PUFAs is built on faulty epidemiology

0:56:21 0:50:04 Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failurehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/

Transcript

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0:00.0	Welcome to the Fundamental Health Podcast. I'm your host, Dr. Paul Saladino. This
0:10.6	podcast is the result of my relentless search to understand and correct the roots of chronic
0:15.1	disease and illness. In this podcast, I will share with you everything I have learned
0:19.0	about how to live the most healthy and radical life possible. Thanks for joining me on this
0:23.4	journey.
0:27.2	What is up, you guys? Welcome to another week of the Fundamental Health Podcast and
0:31.5	welcome to Nose to Tail November. If you got my newsletter, which you can sign up for
0:36.6	at heartandsoil.co, you'll know that it's Nose to Tail November. Just excited about doing
0:43.8	this for the first time to help us all remember and celebrate in this month of gratitude
0:48.2	and Thanksgiving, the bounty, the nourishment that Oregon's provide for us. So you can go
0:53.4	to our website, heartandsoil.co, front slash November to sign up for Nose to Tail November.
0:59.0	I'll be sending out emails every Monday, just kind of encouraging people, talking about
1:03.1	how it's going for us, sharing your stories, and talking about specific Oregon's and why
1:07.0	they're beneficial. We're going to be giving away three signed copies of my book and some
1:11.4	free supplements to participants. So join us. There are now already a ton of people signed
1:18.0	up and we're just excited to share it. There's a hashtag, Nose to Tail November that you can
1:21.7	share on socials. But join us in appreciating the nourishment that animals give us when
1:27.2	reading the Nose to Tail. This is a part of the remembering. It's a big part of I think
1:33.0	what I believe in. It's just super exciting stuff. And the more I think about it, the more
1:37.7	I really continue to believe that we've lost a lot of what it means to be human. And
1:43.7	though we're always evolving and changing as humans, I think that we find the most health
1:48.8	and happiness. And I mean those very sincerely, truly finding health and happiness and meaningful
	...

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