734: Exosome Revolution: Understanding Quality, Bioactivity, and Red Flags
Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™
Kay Durairaj, MD, FACS @beautybydrkay
5 • 604 Ratings
🗓️ 3 June 2025
⏱️ 48 minutes
🧾️ Download transcript
Summary
Discover what exosomes really are – tiny nano-bubbles secreted by stem cells, packed with rejuvenating ingredients. Learn why the source of these stem cells, particularly age-zero Wharton's jelly from umbilical cords, is paramount for optimal regenerative potential. The experts delve into the vital differences between truly bioactive exosomes and ineffective products, highlighting common pitfalls such as the absence of medical-grade certification, lack of comprehensive donor history, and the detrimental impact of high stem cell passages or lyophilization (freeze-drying).
Equip yourself with the critical understanding of exosome safety, quality, and testing protocols, so you can confidently choose providers who meet the highest standards in this burgeoning field.
Transcript
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| 0:00.0 | Well, hello, hello, guys. You're listening to Beauty Bites with Dr. K, secrets of a plastic surgeon, |
| 0:20.7 | and it's time for a really |
| 0:22.9 | interesting podcast. I know you guys have heard the buzzword exosomes. Exosomes are everywhere in |
| 0:28.9 | aesthetics in your Durham office, your plastic surgery office, and we have two really amazing experts |
| 0:34.9 | today. We're going to talk about all the red flags and all the safety |
| 0:38.0 | issues you should be aware of with exosomes that are on the market. So I want to welcome Aaron Crowley |
| 0:42.7 | and Dr. Mike Hecke and we are going to talk in detail. Aaron is a global leader in regenerative |
| 0:49.5 | biotherapeutics. She's co-chair of the Exosome Exact Oversight Bureau and a co-manager of the Crowley Center for Regenerative Biotherapeutic. |
| 0:59.6 | She has more than 15 years of experience in the corporate world, engineering, and regulatory compliance. |
| 1:05.1 | And she's bringing those gold standards into aesthetics. |
| 1:08.9 | This year, she's really worked on pioneering a new era of purity, |
| 1:14.6 | functionality, transparency, and really looking at what makes a gold standard for an exosome |
| 1:20.1 | in terms of exosome quality. So she's at the helm of this exosome exact oversight bureau, |
| 1:25.6 | which we're going to hear more about. And Dr. Mike Hecke started his |
| 1:29.0 | career in pharma researching with Bayer, and he has been a stem cell researcher since the year 2000, |
| 1:35.9 | and did stem cell work in heart failure. He was also a scientific coordinator for many |
| 1:41.3 | large-scale EU projects. He founded the German stem cell network, |
| 1:45.8 | and he joined Rockefeller University to lead its Department of Stem Cell Biology. He was appointed |
| 1:52.2 | deputy to the president of Stanford University managing Bing's presidential laboratory. |
| 1:57.5 | And he also is currently at the Crowley Center for Regenerative Biotherapeutics, and they focus on |
| 2:02.5 | kind of bringing stem cell science safely and effectively into regenerative medicine. |
| 2:07.2 | So with that huge intro, you guys know you're listening to some experts. |
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