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Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

711: All About Exosomes - A Game Changer?

Beauty Bytes with Dr. Kay: Secrets of a Plastic Surgeon™

Kay Durairaj, MD, FACS @beautybydrkay

Health & Fitness, Medicine, Arts, Management & Marketing, Fashion & Beauty, Business

5604 Ratings

🗓️ 14 March 2025

⏱️ 10 minutes

🧾️ Download transcript

Summary

It's Five Minute Friday! 

Today we're taking a deep dive into Exosomes. What are Exosomes? Where do they come from? What are the benefits of using Exosomes dermally and are they safe to use subdermally? 

We'll talk about FDA regulations when it comes to Exosomes being approved for injections and what that roadmap looks like. 

Transcript

Click on a timestamp to play from that location

0:00.0

Well, hello, hello, guys. You're listening to Beauty Bites with Dr. K., Secrets of a Plastic Surgeon,

0:17.7

and it's time for a five-minute Friday day today i want to talk about exosomes i

0:23.9

don't know if you guys have been to aesthetic meetings but everywhere you look in aesthetics there are

0:29.2

companies popping up with exosomes and for patients out there who are seeing providers you might

0:35.3

be starting to see the word exosome used more often in

0:38.3

treatments, either before or after getting an intervention like before. Sometimes we'll do exosomes

0:45.1

prior to treatment to improve and heal redness and irritation of skin, and for other patients

0:50.8

will use them post-treatment, after laser, after microneedling, after procedures

0:55.6

that stimulate skin barrier irritation, exosomes are products that can definitely help you to

1:01.1

heal faster and better. But exosomes, what the heck are they? This is so exciting. They are a very

1:09.4

interesting addition to regenerative aesthetics and the whole portfolio of what we can do for people.

1:14.8

An exosome is a lipid bi-layer extracellular vesicle. That's a mouthful. So it's a little particle made of lipids on the outside and on the inside there is important messaging material these little

1:29.8

bubbles or vesicles carry messages like growth factors they have mRNA they have sometimes

1:36.9

small fragments of peptides and amino acids in them they're a mixture of signals basically, exosomes can be derived from many different

1:45.8

sources. When we're looking at the sources of these exosomes, we need to be concerned about, number

1:51.6

one, where are they getting their product and donations from? So what type of donor product is

1:58.3

used? Exosomes can definitely come from fat, platelets, bone marrow, umbilical cords, placenta, plants.

2:07.3

There's so many different sources of where exosomes can come from.

2:11.3

We really have to think carefully about the source of the exosome

2:14.6

when we're trying to understand the powerful use of the exosome.

2:18.3

So if, for example, I'm going to be working on hair, I might like to use an exosome derived

2:23.5

from hair type of follicular cells or from platelets, which platelet derived growth factor has

...

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