691: Scientist Reveals Why Glycine Is Key to Turning Off Inflammation | Dr. Joel Brind
The Jesse Chappus Show
Jesse Chappus
4.6 • 1.6K Ratings
🗓️ 10 February 2026
⏱️ 109 minutes
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Summary
Joel Brind, PhD, is a Yale-educated life scientist who has spend his life in medical research.
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Transcript
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| 0:00.0 | Coming up on today's show. |
| 0:02.1 | Contrary to what it says in any source you look at, |
| 0:05.4 | that inflammation is the immune system's first response to infection or injury, |
| 0:09.7 | it is really only a first response to infection. |
| 0:13.3 | Inflammation does the body no good whatsoever in the case of injury. |
| 0:17.4 | And if you have enough glycine, it won't happen. |
| 0:19.7 | And you will feel better for it and |
| 0:21.6 | live better for it. Every element of modernity in terms of diet has worked against health because |
| 0:28.6 | it's worked toward lowering the naturally high levels of glycine that we should have with a really |
| 0:33.6 | healthy diet. There's an M1 macrophage and an M2 macrophage. And the M2 is quiesin. It will go |
| 0:39.2 | around and phagocetize like a little army of amoebas. It will clean up dead cells and cell debris, |
| 0:44.7 | but it will not trigger this secretion of poisons designed to kill whatever it is that got into |
| 0:50.2 | you. That won't happen unless it's activated to M1. M1 is starting to shoot the place up with all these |
| 0:56.1 | poisons. Unless there is a bad actor present, then they will do their inflammation thing and try to |
| 1:02.1 | clear the infection. But if there is no infection, why are they going to do that? Glycine, we need more |
| 1:07.5 | than we're getting. We cut the muscle meat off the bone. We throw the bones in the trash instead of in the soup. |
| 1:12.4 | Therefore, as part of a really healthy optimal diet, we need to take a supplement of glycine. |
| 1:17.9 | I believe everyone needs it for health and general sense of well-being. |
| 1:22.7 | Joel, starting back in 2008, you began supplementing with 10 grams of glycine a day. |
| 1:31.5 | Share with me the backstory that led to that experiment. |
| 1:35.4 | Well, okay. |
| 1:36.2 | Well, the backstory is basically research that I was doing with a private research foundation. |
... |
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