652. Biohacking Built for You: Using DNA to Optimize Supplements, Diet, & Training w/ Kashif Khan
The Life Stylist
Luke Storey
4.7 • 2.1K Ratings
🗓️ 24 February 2026
⏱️ 100 minutes
🧾️ Download transcript
Summary
In this episode, I dive deep into one of my favorite topics—bio-individuality—and why your genes may hold the missing key to your health struggles. Kashif Khan joins me to unpack how his own health crisis at 38, marked by eczema, psoriasis, gut issues, depression, and debilitating migraines, sent him down a rabbit hole that ultimately led to genetics. What he discovered completely reframed the way he thought about wellness.
We explore how two people can eat the same food, live the same lifestyle, and experience radically different outcomes—and why that discrepancy often comes down to gene expression. Kashif breaks down dopamine pathways, addiction tendencies, trauma imprinting, and how certain genetic profiles can be both a superpower and a liability depending on context. If you’ve ever wondered why you’re wired the way you are or why certain habits feel nearly impossible to break, this conversation will hit home.
We also get into estrogen metabolism, detox pathways, hormone replacement therapy, environmental toxins, and the shocking role negative emotions play in turning disease-related genes on. One of the biggest takeaways for me was how ancestral habits, geography, and even generational trauma can influence which genes are expressed.
This episode is a powerful reminder that health isn’t about chasing trends—it’s about understanding your unique blueprint. If you’re tired of guessing and ready to personalize your approach to fitness, supplements, hormones, and longevity, this one is going to open your eyes in a big way.
Join the free DNA Five Pillar Program webinar and live Q&A with Kashif and me on March 4 at 7:30 pm Eastern Time/6:30 pm Central Time. You can visit www.hackmydna.com/lukestorey to sign up.
DISCLAIMER: This podcast is for educational purposes only and not intended for diagnosing or treating illnesses. The hosts disclaim responsibility for any adverse effects from using the information presented. Consult your healthcare provider before using referenced products. This podcast may include paid endorsements.
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MORE ABOUT THIS EPISODE:
(00:00:00) From Health Crisis to Genetic Awakening
(00:17:04) Ethnicity, Epigenetics, & the Hidden Code Behind Resilience
(00:43:32) Why the Same Healing Tool Works for Some People—and Fails Miserably for Others
(01:01:37) Cold Plunges, Hormone Cycles, & the Genetic Case for Personalized Biohacking
(01:14:17) The Truth About DNA Testing, Data Ownership, & Why Personalization Beats Trial-and-Error
Resources:
• Website: kashkhanofficial.com
• Website: thednacompany.com
• Instagram: instagram.com/kashkhanofficial
• Facebook: facebook.com/thednacompany
• X: x.com/mrkashkhan
• TikTok: tiktok.com/@kashkhanofficial
• YouTube: youtube.com/@thednacompany4669
• Shop all our merch designs at lukestoreymerch.com
• Join me on Telegram: t.me/lukestorey
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Medical research doesn't study healthy people and ask them why didn't you get sick? |
| 0:03.1 | I did both. There isn't a choice that we can discuss today that can't be filtered through the genome to personal. |
| 0:10.3 | This is what's missing from healthcare research. They're medical professionals that hate what they're doing |
| 0:14.3 | and want this training for their patients because they can't get it from their college. |
| 0:17.6 | If I have your DNA, I can tell you how sick you're going to get from a. |
| 0:40.3 | The average person is seeing 90%. The 95%, they're seeing a little less than what's actually going on. Now, imagine the person who sees 130% that sees literally every little nuance, every little detail, and thinks that's what everybody else is also experiencing. It's no longer about perspective. It's about right and wrong. If you take control of the things that cause the problem, but we just don't know what those things are, but your DNA tells you. |
| 0:46.3 | So you hit a health wall when you were about 38. I'd like to hear about what contributed to that |
| 0:53.3 | and what you found out. |
| 0:55.4 | Because I find that people that are really committed to helping people in the health space |
| 1:00.8 | often have some origin story that involve them reaching a place that got scary and |
| 1:08.9 | force them to make some changes or start to research outside of the box. |
| 1:12.8 | That's the classic functional medicine story, right? |
| 1:16.4 | Like nobody could help me. |
| 1:17.5 | I helped myself and here the world needs to know, right? |
| 1:20.3 | So yeah, I believed I was sick because me and my business partner who worked together, |
| 1:26.4 | we drove to work together, lived on the same |
| 1:28.4 | street, we're the same age, same ethnic background, we ate lunch together, we ate dinner together |
| 1:33.0 | because we worked so hard. And I had eczema to the point where I couldn't open my eye. |
| 1:37.4 | It was like sealed shut from inflammation, my left eye, psoriasis, gut issues, depression, didn't |
| 1:43.7 | want to go to work on some days. |
| 1:45.1 | And what really sent me to the doctor was migraines. |
| 1:47.6 | That was the thing that I couldn't fight through, just deabilitating. |
... |
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