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The After On Podcast

62: "DEEP VZN" Revisited | Kevin Esvelt

The After On Podcast

Rob Reid

Science, Technology

4.92.1K Ratings

🗓️ 11 March 2026

⏱️ 114 minutes

🧾️ Download transcript

Summary

I'm reposting my 2022 interview with Kevin Esvelt on the deranged USAID program "DEEP VZN," in conjunction with my latest appearance on Sam Harris's podcast, in which we discuss this terrifying topic

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the AfterOn podcast. I'm your host, Rob Reed, bringing you conversations with thinkers, founders, and scientists. They're in-depth and unhurried and are structured to bring you up to a top percentile understanding of something important. So, whether you're into startups or ideas, a techie or a lit major, take your time,

0:25.6

engage your mind, and you'll be glad you did.

0:32.9

This is a reposting of an episode I first ran way back in 2022.

0:39.3

It's an interview with MIT's Kevin Esfeldt about an insanely misguided virology research program called Deep Vision. USAID

0:46.3

spun up Deep Vision with a $125 million budget, and it had insane destructive potential. Had it delivered

0:53.9

on its objectives, I find it impossible

0:56.5

to imagine a scenario in which it wouldn't have triggered untold millions of deaths. These awful

1:02.5

consequences may or may not have come quickly, but they definitely would have come over time.

1:07.9

This interview was my attempt to blow the whistle on Deep Vision. I was greatly assisted in this

1:12.6

by Sam Harris, who also posted my episode to his much larger audience. I'm about to appear on

1:18.5

Sam's podcast again to discuss Deep Vision and how it was shut down. And above all, the lessons we

1:24.2

urgently need to learn from this outlandish near miss as we approach a much

1:29.1

more fractured and alarming risk landscape than we faced back then, driven by the collision

1:34.4

of AI and synthetic biology. So I thought it would be useful to repost this interview that

1:40.3

touched everything off. As a context for my own audience, who may want to check out my

1:44.6

appearance on Sam's podcast, and maybe for some of Sam's listeners who might find their way here

1:49.1

to get the full Deep Vision story. Back to the history. After Sam and I first posted this interview

1:55.2

with Kevin, some people reached out to me who, unlike Kevin, me, or Sam, knew how to navigate Washington. They discovered

2:02.7

that some influential people were already sniffing around Deep Vision. Then they quickly assembled a

2:07.4

remarkably diverse alliance, both politically and in terms of professional backgrounds.

2:12.9

Eventually, Deep Vision was defanged before it could do any damage, and quite some time after that, it was fully

2:19.0

and formally terminated. No one person took the kill shot. Instead, lots of pressure, emitting from

...

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