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The Dr Louise Newson Podcast

59 - Can you start HRT after 60? What the evidence shows

The Dr Louise Newson Podcast

Dr Louise Newson

Health & Fitness, Medicine

4.7933 Ratings

🗓️ 21 April 2026

⏱️ 28 minutes

🧾️ Download transcript

Summary

So many women are denied hormone replacement because they are told they are “too old”.


In this special solo episode, Dr Louise Newson explains why this is wrong. She covers what happens when hormone levels stay low as women age and why this long-term deficiency affects everything from cardiovascular health to bone strength and cognitive function.


She clarifies why the WHI study created so much confusion, how its findings differ from modern body-identical HRT and what starting treatment in your 60s or beyond realistically looks like. It’s a clear, current overview for anyone told they’re “too old” for hormone therapy.

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Transcript

Click on a timestamp to play from that location

0:00.0

There are many benefits of taking hormones, as many of you know, but one of the questions that

0:04.8

comes up a lot is, can I take HRT if I'm over the age of 60? So I want to unpick this because

0:11.2

it causes so much confusion and I don't think it should. So let's think about hormones first.

0:18.3

And when I talk about hormones, I'm only talking about three

0:21.6

of dozens of hormones we have in our body. So we've got progesterone. We've got estradiol and testosterone.

0:28.7

And they're made in our ovaries. They're made in our adrenal glands. They're made in our brains.

0:33.9

And they're made in other organs and tissues. And as you know, they're chemical messengers.

0:38.1

So they go into our bloodstream and they affect every single cell in our body. They have really

0:43.2

important biological actions in our cells to keep us healthy, like our other hormones do.

0:50.6

But when we become menopausal, the levels of these hormones reduce and decline, and then they

0:56.6

stay low forever. Now, because we still produce hormones in other tissues, we are still getting

1:04.2

some hormones, and because our other hormones are biologically active, they can often take

1:10.1

some of the jobs of our other hormones, but not all

1:14.0

of them. So we have receptors on us on our each cell that are specific for each hormone. So we have

1:21.5

a progesterone receptor. We have an esterile receptor. In fact, we have two of them. And we have

1:27.4

testosterone receptors.

1:29.4

And as you know, I'm sure as well, is that our cells are constantly being remade. Like if you

1:35.1

think about just our skin, we're constantly shredding skin cells from our outside of our skin

1:41.2

and our body's making new ones all the time. Our bone is dynamically active.

1:46.1

We're building new bone and breaking down bone all the time and repairing. Our blood vessels

1:51.9

are regenerating. In our brains as well, we are forming new brain cells all the time. And all of

1:59.5

these cells have receptors for these hormones in them

...

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