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The Genius Life

533: How to Ease Inflammation and Support Your Brain, Heart, and Joints Naturally | Dave Watumull

The Genius Life

Max Lugavere

Health & Fitness

4.74.7K Ratings

🗓️ 10 December 2025

⏱️ 80 minutes

🧾️ Download transcript

Summary

Dave Watumull joins me to explain how a natural red nutrient called astaxanthin found in wild salmon may help reduce inflammation, boost recovery, and support healthy aging.

Note: AX3 sponsors this episode but did not influence its content.

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This episode is proudly sponsored by:

AX3 Life produces highly bioavailable astaxanthin, dubbed the king of carotenoids and a “longevity vitamin.” Visit http://ax3.life and use code MAX for 20% off.

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Transcript

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0:00.0

What up, friends? It's episode 533 of The Genius Life. Let's go.

0:06.2

What's going on, everybody? I'm your host, Max. What's going on, everybody? I'm your host, Max. Life, The Genius Life.

0:24.2

What's going on, everybody?

0:27.6

I'm your host, Max Lugavir, and welcome back to The Genius Life, the show where we try to live longer, feel better, and try not to collaterally damage our mitochondria in the process.

0:32.5

Today, we're diving deep into what might be the most slept-on longevity nutrient in existence,

0:36.9

astazanthan. My guest is Dave

0:38.8

Wadamol, co-founder and CEO of AX3, and one of the people most obsessively dialed in on this molecule

0:44.8

on the planet. In this conversation, we unpack why astazanthin is the only natural compound so far to

0:50.4

extend lifespan in the NIH's gold standard interventions testing program and have a safety

0:55.4

profile that makes sense for daily use, plus decades of human data on skin, eyes, brain, heart,

1:01.1

joints, endurance, and more. We get into why this carotenoid is so unique from how it literally

1:05.9

spans your cell membranes to protect them from oxidative stress and chronic inflammation,

1:10.0

to what that means in the real world for things like rheumatoid arthritis, VO2 Max, digital eye strain in kids,

1:16.1

and even muscle preservation as you age. Dave breaks down complex pathways like AMPK, autophagy,

1:22.4

and mitochondrial function in plain English. We talk dosing, including what I personally take, how to track its

1:28.4

impact with labs like HSCRP and oxidized LDL, where it fits into a smart longevity stack alongside creatine and omega-3s, and why I think of it as a legit longevity vitamin. Now, full disclosure, AX3, which is Dave's company, is also a partner of the show, but they make the Astizanthan that I personally use. Their AX3 formulation is ultra pure, oil-free, and highly bioavailable. If you want to try it out for yourself, you can head to AX3.com and use code max for 20% off of your order. Now, with all that out of the way, listen all the way through to the end. You're not going to want to miss a beat. and as always don't forget to share this episode with friends and loved ones who you think might benefit from it.

2:02.2

Oh, one last thing before I forget, Dave actually breaks open an AX3 capsule and shows us the beautiful red pigment imparted by this incredible compound. So if you're listening on Spotify, it's a great opportunity to hit the video on button or to check us out on YouTube. All right, guys, let's dive in. Dave Watermore,

2:18.3

welcome back to the show. How you doing? Thanks. I'm great. It's great to be here.

2:21.3

Fresh off the plane from Hawaii to school us all on the mystical, seemingly mystical powers of

2:29.3

this powerful carotenoid astazanthan, which my audience knows I'm a huge fan of. And you are the goate when it

2:35.7

comes to all things astisanthan and more broadly carotenoid science. So I'm excited to get into it,

2:41.8

but I love to just dive right in. If you had to explain to a 12-year-old why this one carotenoid

...

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