Today on Talk Python, what really happens when your data work outgrows your laptop?

Matthew Rockland, creator of Dask and co-founder of Coiled, and Nat Tabri, a staff software

engineering coiled, joined me to unpack the messy truth of cloud-scale Python.

During the episode, we actually spin up a 1,000-core EC2 cluster from a notebook twice.

We also discuss picking between pandas and polars, when GPUs help,

how to avoid surprise cloud bills, real lessons, real tradeoffs shared by people who have built this stuff.

Stick around.

This is Talk Python to Me.

Episode 519 recorded August 26, 2025.

Talk Python to me. Yeah, we ready to roll. Upgrading the code. No fear of getting old.

Hey, sink in the air. New frameworks in sight. Geeky rap on deck. Quark crew. It's time to

unite. We started in pyramid cruising old school

name a weekly podcast on python this is your host michael kennedy follow me on massadon

where i'm at m kennedy and follow the podcast using at talk python both accounts over at fostodon.org

and keep up with the show and listen to over nine years of episodes

at TalkPython.fm. If you want to be part of our live episodes, you can find the live

streams over on YouTube, subscribe to our YouTube channel over at talk python.fm slash

YouTube and get notified about upcoming shows. This episode is brought you by Century.

Don't let those errors go and

notice. Use Century like we do here at TalkPython.com.com.com.com.com slash Century. Matthew, Nat. Welcome to the show. Awesome. Have you here. Hey, Michael. Good to be here. Thanks. It's been a while, Matt, since you've been on the show. Every year or two, we got to chat. you and I chat a conference sometimes too.

It's always good to see you.

Absolutely. Yeah, it's always really good to see you as well.

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