#474 Resistant Hypertension the Next Frontier

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 10 March 2025

⏱️ 77 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Treat Hypertension Like No Doctor Has Ever Treated Hypertension Before

Treating hypertension never gets boring. Learn about emerging therapies and how to continue to tackle this common diagnosis like a pro. Dr. Jordy Cohen (@jordybc.bsky.social) leads us through her approach to keeping the BP where it should be (University of Pennsylvania).

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Show Segments

00:00 Introduction and Current Interests
01:55 Understanding Hypertension
11:59 Blood Pressure Measurement Techniques
19:58 Treatment Goals and Guidelines for Hypertension
30:02 Managing Resistant Hypertension and New Treatments
36:00 Exploring GLP-1 Agonists and Blood Pressure Benefits
39:06 Aldosterone Synthase Inhibitors: A New Hope
42:00 Innovative Approaches: Small Interfering RNAs in Hypertension
47:06 Renal Denervation: A Controversial Procedure
55:01 Understanding Resistant Hypertension and Testing Protocols

Credits

Writer and Producer: Deborah Gorth MD, PhD
Show Notes: Ben Furman and Deborah Gorth MD, PhD
Cover Art and Infographic: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai Achi MD, MBA, FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Jordana Cohen MD, MSCE

Disclosures

Dr. Jordana Cohen and The Curbsiders report no relevant financial disclosures.

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Transcript

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0:00.0	Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.com
0:05.5	slash curbsiders.
0:06.7	If you haven't signed up yet, sign up now to get ad-free episodes, twice-monthly bonus episodes,
0:11.9	and a whole bunch of other cool stuff at patreon.com slash curbsiders.
0:19.2	Did you hear about the group of boats which crushed each other against their mooring structure?
0:29.9	No, Matt. Tell me about them.
0:32.2	It was yet another casualty of peer pressure.
0:37.4	Okay. Pier. Yeah, no, I got it. I was trying to... casualty of peer pressure.
0:37.9	Okay.
0:38.9	Pier.
0:41.0	Yeah, no, I got it.
0:44.3	I was trying to make Armada work, and I thought, well, that's probably not it.
0:45.2	And I was drawing for fleet.
0:45.9	That didn't happen.
0:49.9	I did try to, I looked up aldosterone pun, Matt.
0:54.4	And Google's just like, nope, I'm not even like the decision. Here's what Aldosterone does.
0:57.2	So Google AI is giving up on me.
0:59.9	Yeah, we're, audience, we're running out of puns.
1:00.5	Deal with it.
1:05.4	The curbsiders podcast is for entertainment, education, and information purposes only.
1:13.5	And the topics discuss should not be used solely to diagnose, treat, cure, or prevent any diseases or conditions. For the more, the views and statements expressed on this podcast are solely those of those and should not be interpreted to reflect official policy or position of any entity, aside from possibly cash like a moral hospital and affiliate outreach programs.
1:15.2	If indeed, there are any.
	...

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