#472 DIGEST: cfDNA & cancer in Pregnancy, Vitamin K2 for Leg Cramps, PRN anti-hypertensives, GLP-1 Agonists for AUD, Short-Course Antibiotics

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 24 February 2025

⏱️ 54 minutes

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Summary

Join us as we review recent articles and news featured in The DIGEST issues #59-61, including cfDNA and incidental detection of cancer in pregnancy, vitamin K2 for nocturnal leg cramps, the danger of as-needed anti-hypertensive medications in the hospital, GLP-1 agonists for alcohol use disorder, short-course (7 vs 14 days) antibiotics for bacteremia, and patient-collected HPV testing for cervical cancer screening. Fill your brain hole with a fully digestible meal! Featuring Laura Glick MD, Nora Taranto (@norataranto), Paul Williams (@paulnwilliamz), and Matt Watto (@doctorwatto).

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Show Segments

00:00 Introduction and Overview
02:57 The IDENTIFY study: Non-Invasive Prenatal Testing and Cancer Detection with cfDNA
05:54 Implications of Non-Reportable Results in Prenatal Testing
08:51 Vitamin K2: A New Approach to Managing Nocturnal Leg Cramps
12:07 Practicality and Future of Vitamin K2 in Clinical Practice
23:21 The Dangers of As-Needed Antihypertensives in the hospital
32:21 Exploring GLP-1 Agonists for Alcohol Use Disorder
40:24 Shorter Antibiotic Courses in Sepsis
46:09 Advancements in Patient-Collected HPV Screening for cervical cancer

Credits

Written and Produced by: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP
Show Notes: Nora Taranto MD
Cover Art: Matthew Watto MD, FACP
Hosts: Nora Taranto MD, Laura Glick MD, Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Emi Okamoto MD
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste

Disclosures

The Curbsiders report no relevant financial disclosures.

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Transcript

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0:00.0	Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.
0:04.4	at patreon.com slash curbsiders. If you haven't signed up yet, sign up now to get ad-free episodes,
0:10.2	twice-monthly bonus episodes, and a whole bunch of other cool stuff at patreon.com slash
0:15.4	curbsiders. Hey, Paul, my friend has fallen head over heels for a new girl.
0:24.5	She's only a humble whiskey maker, but he loves her still.
0:29.1	That's not bad.
0:32.1	Matt, I was talking to a Frenchman, a man from France, and I asked him if he liked video games. And do you know
0:38.7	what he said to me? I don't know. We. I feel like that's pretty solid. Yeah, okay.
0:48.6	All right. The Curbsiders podcast is for entertainment, education, and information purposes
0:53.4	only and the topics discussed should not be used solely to diagnose, treat, cure, or prevent any diseases or conditions.
0:57.1	For the more of the views and statements expressed on this podcast are solely those of the host and should not be interpreted to reflect official policy or position of any entity.
1:01.3	Aside from possibly, cash like a more honest, and affiliate outreach programs.
1:03.5	If indeed, there are any.
1:04.5	In fact, there are none.
1:05.3	Pretty much, we are responsible if you screw up. Always do your own homework and let us know.
1:17.3	Welcome back to the curbsiders.
1:22.5	I'm Dr. Matthew Frank Guaddo here with my great friend and America's primary care physician,
1:29.6	probably the primary care physician, Dr. Paul Nelson Williams. Hey, Paul. How are you doing tonight?
1:34.7	I'm great, Matt. How are you doing? I'm doing well, because this is a digest episode. It's been quite a while since we did one of these. We got some great articles to talk about some practice
1:39.7	changing. Maybe all of them practice changing. We'll decide in real time. And we have two great
1:45.2	friends with us to help us do this, Paul. But before we introduce them or before you introduce them,
1:50.9	remind people, what is it that we do on curbsiders? Sure, happy to, Matt. As a reminder, we are
	...

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