meta_pixel
Tapesearch Logo
Log in
Commune with Jeff Krasno

462. The Gut-Brain Connection: How Stress, Trauma, and Shame Impact our Physiology with Dr. Will Cole

Commune with Jeff Krasno

Commune Media

Health & Fitness, Society & Culture

4.6 β€’ 654 Ratings

πŸ—“οΈ 27 July 2023

⏱️ 120 minutes

🧾️ Download transcript

Summary

Leading functional medicine expert Dr. Will Cole discusses how chronic stress, unresolved trauma, and shame can dysregulate the neuroendocrine axis, leading to hormonal imbalances and inflammation. Discover the role of gut health, environmental toxins, and social media in shaping our well-being, and learn practical strategies to support healing, improve vagal tone, and cultivate resilience.

In this episode we cover:
0:04:50 – The Gut + The Nervous System
0:07:20 – The Vagus Nerve
0:11:14 – Gut-Brain-Axis
0:13:20 – Hormones
0:17:44 – Mood
0:21:26 – Bacteria
0:24:07 – Intestinal Permeability
0:26:21 – Maintaining Good Gut Flora
0:35:51 – Antibiotics
0:37:19 – How to Upregulate Gut Function
0:41:44 – Psychology and Physiology
0:43:01 – Metaphysical Meals
0:46:02 – Shame
0:47:20 – Fight or Flight
0:51:18 – Shameflammation
0:55:23 – Loneliness
0:59:48 – Epigenetics
1:05:47 – Gut Feelings Protocol
1:15:35 – Recipes


Learn more about Commune and check out all our health, nutrition, and functional medicine courses free for 14 days at onecommune.com/trial

This podcast is supported by:


Big Bold Health
Big Bold Health has just released its ultimate immune synergy combo of its top immune
active ingredients from plants, sea, and soil. Featuring clinically studied probiotics, prebiotics, and supercharged omega-3s. Big Bold Health is offering the Commune community $10 off most products when you go to bigboldhealth.com and use the promo code β€œCOMMUNE”.

Parsley Health
It’s time to get better and feel better. Go to parsleyhealth.com/commune to schedule a free membership consultation and learn more about how Parsley can help you heal.

Vivobarefoot
Vivobarefoot is giving feet the freedom to move as Mother Nature intended. The best piece of technology ever to be put into a shoe is the human foot. Get 15% off your first Vivobarefoot order at Vivobarefoot.com. Use the code VIVOCOMMUNE15 at check out. Reclaim your natural potential. The journey starts with your feet.

Apollo Neuro
The Apolloβ„’ wearable uses scientifically-backed touch therapy to rebalance your nervous system and support your circadian rhythm. Sleep better, feel calmer, find focus, and get energized with this groundbreaking new wearable. SPECIAL OFFER FOR FRIENDS OF COMMUNE: Try the Apollo wearable today and get $40 off your purchase at apolloneuro.com/commune.

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the Commune podcast. My name is Jeff Krasnow. Today on the show, I welcome back Dr. Will Cole.

0:16.0

Will has been named one of the top 50 functional and integrative doctors in the nation and runs one of the

0:23.0

first functional medicine telehealth centers in the world. He specializes in excavating

0:28.8

the underlying root causes of chronic disease and customizing a personalized precision medicine

0:37.2

approach for conditions including thyroid issues,

0:41.3

autoimmune diseases, hormonal imbalances, and digestive and mental disorders. In today's interview,

0:48.4

we discuss the fascinating connection between the gut and the brain. Now, when we were fetuses, just growing in our mother's

0:57.3

womb, the brain and the gut formed from the same exact tissue, linking them for the rest of

1:03.2

our lives through what is known as the gut brain axis. Now, you may have heard the term

1:09.6

vagal tone being thrown about the zeitgeist. Well, it refers to the

1:14.3

activity of the vagus nerve or wandering nerve. This is the largest cranial nerve in the body.

1:21.5

And this nerve serves as a bidirectional highway for communication between the gut and the brain.

1:28.3

So improving vagal tone has far-reaching implications on overarching health,

1:33.3

including enhancing mood, upregulating immune system and digestion and energy levels.

1:39.3

So in our conversation, we dive into the connection between the physiological and the psychological, which is the topic

1:46.2

of Will's latest book, gut feelings, healingly shame-fueled relationship between what you eat

1:52.6

and how you feel. Clinical studies show us that chronic stress, unresolved trauma, shame,

2:00.3

and environmental toxicity can impact the body's

2:03.5

underlying biochemistry, creating chronic inflammatory problems and metabolic and brain health

2:11.0

issues. Now, the fight or flight response is a natural adaptive biological feature, but

2:17.1

modernity has created an evolutionary mismatch.

2:21.4

And when we're exposed to chronic stress, the HPA axis, that's the hypothalamic pituitary

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Commune Media, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Commune Media and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright Β© Tapesearch 2025.