Hello and welcome to another episode of Sigma Nutrition Radio. I am your host, Danny Lennon.

This is episode 399 of the podcast. You are very

welcome. On today's episode, I'm going to be talking with Professor James Betts, who is

Professor of Metabolic Physiology at the University of Bath, where he is the co-director of the

Center for Nutrition Exercise and Metabolism

there. And his research employs randomized control trials to study the effects of

nutrition on metabolic regulation. And this has spanned a wide variety of different interesting topics.

But today we're specifically going to focus in on the impact of fasting on

health with and without weight loss. And that was the question that was attempted to be answered

by a recent study that came from Professor Betts's group. So this was a randomized control trial

titled, A Randomized Control Trial to Isolate the Effects of Fasting and Energy Restriction on Weight Loss and Metabolic. as groups. So this was a randomized control trial titled a randomized controlled trial to isolate the

effects of fasting and energy restriction on weight loss and metabolic health in lean adults.

And that's going to be the primary focus of today's discussion to get into what that paper

found and some of the big takeaways from that trial, as well as some other thoughts about fasting more

generally, how we should define that, and just how we should be better at appraising the literature

in this area. So I think you're going to find it really, really interesting and informative.

If you want to get the show notes this episode, just go to sigmautrition.com slash episode 399.

There you'll be able to get a link to any studies that we mentioned throughout this episode.

We'll be linked up there. You'll also get an overview of the episode and you'll also

get a transcript of this and previous episodes to the podcast. And whilst you're over on the

website, sigma nutrition.com,

check out some of our other content. We have our written long form Sigma statements,

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