4.8 • 626 Ratings
🗓️ 9 March 2021
⏱️ 77 minutes
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In this episode Danny and Alan discuss some critical aspects to understand about nutritional epidemiology in order to evaluate diet-disease relationships appropriately. Of particular focus in this episode is the unique exposure of interest in nutrition studies, why its crucial to understand temporal relationships and how to think about relative risk and absolute risk. The guys finish by explaining how one can include these findings into an understanding of an overall body of evidence.
Show notes: sigmanutrition.com/episode378
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0:00.0 | Okay, here we are. Welcome to episode 377 of Sigma Nutrition Radio. My name is Danny Lennon. I'm here with Alan Flanagan. |
0:22.6 | I think, well, we had our big bit of excitement with our sodium episode, which was people seem to enjoy. |
0:29.6 | And there was actually a lot of good discussion and comments off the back of that. So thanks for anyone who sent that. |
0:35.6 | But actually, today's episode, I think, is going to be useful to tie some of that together So thanks for anyone who sent that. But actually today's episode, I think, is going to be |
0:38.7 | useful to tie some of that together. Not only the sodium episode, but in episodes where we've |
0:44.8 | dealt with dietary cholesterol or LDL cholesterol or other aspects of nutritional science, |
0:51.2 | specifically in these diet disease relationships, and to try and kind of zoom out and at a higher level understand nutritional science specifically in these diet disease relationships and to try and kind of |
0:55.0 | zoom out and at a higher level understand nutritional science a bit. Now of course we've done a |
1:00.8 | similar episode like this in relation to meta-analyses and today's conversation we're going to |
1:05.7 | look at nutritional epidemiology specifically. These conversations I think are quite important because they're not |
1:13.7 | often had but I think they lay the groundwork for being able to really get to grips with |
1:19.5 | some of those concepts we discussed, for example, in the Sony episode of understanding these |
1:24.0 | diet disease relationships, looking at assessment methods, or how we are able to integrate |
1:30.3 | these into a bigger picture of risk. So I think this will hopefully prove useful to people. |
1:36.3 | Yeah. So I think, I mean, just going from first principles with epidemiology, we're talking about the study of like the distribution of disease and the |
1:46.7 | determinants of disease in a human population and the prevalence and incidents and how that |
1:52.7 | prevalence and incidence is of a given disease is influenced by factors that we think might |
1:58.7 | have a relationship with that particular disease process. |
2:01.6 | And with nutrition, we're faced with a particular logistical challenge in that the diseases that we would call chronic diseases, |
2:16.6 | cardiovascular disease, type 2 diabetes, |
2:19.6 | you know, neurodegenerative disease, and cancers are diseases that largely have long latency |
2:26.6 | periods, i.e. they take a long time to develop. And the processes that influence the incidence of that disease later in life can be at play |
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