352 | Bing Brunton on Connecting the Connectome to the Body
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
Sean Carroll
4.7 ⢠4.7K Ratings
šļø 27 April 2026
ā±ļø 77 minutes
šļø Recording | iTunes | RSS
š§¾ļø Download transcript
Summary
The connectome is the wiring diagram of a brain, a big matrix that tells us what neurons talk to what other neurons. Understanding it is an important step to understanding how brains work, but a long way from the final answer. A big next step is understanding how neuronal circuits connect to and guide bodily behavior. Very recent work on mapping the fruit-fly connectome has brought us closer to that goal. I talk with neuroscientist Bing Brunton about the connectome, how we can study it to understand bodily motion in flies and other creatures, and where it's all taking us.
Chubbies is here to keep you comfy and looking good year-round. Get 20% off with codeĀ MINDSCAPEĀ atĀ chubbiesshorts.com/MINDSCAPE! #chubbiespod
Upgrade your denim game with Rag & Bone! Get 20% off sitewide with codeĀ MINDSCAPEĀ atĀ www.rag-bone.com. #ragandbonepod
Support Mindscape onĀ Patreon.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/04/27/352-bing-brunton-on-connecting-the-connectome-to-the-body/
Bing Wen Brunton received her Ph.D. in neuroscience from Princeton University.. She is currently a Professor of Biology and the Richard & Joan Komen University Chair at the University of Washington, with affiliations at the eScience Institute for Data Science, the Paul G. Allen School of Computer Science & Engineering, and the Department of Applied Mathematics.
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Hello, everyone. Welcome to the Mindscape Podcast. I'm your host, Sean Carroll. As you are listening to this podcast or listening to anything else or looking at anything else, your brain is processing information. We can argue about how much information is in the podcast or anywhere else, but in some sense, there are bites of information being sensory inputted into your brain and then processed. |
| 0:25.9 | And that affects what you do, how you behave. |
| 0:29.0 | Now, as we've talked about in the podcast recently, there's other things going on in the brain and the nervous system and the body as well. It's not |
| 0:39.1 | just information processing. There is absolutely information processing happening, but that's an |
| 0:44.2 | abstraction, right? What there's actually happening are atoms, molecules, cells, doing various |
| 0:51.2 | physical things. And we find it very, very interesting and helpful to talk about those physical processes |
| 0:57.8 | in terms of information being processed. |
| 1:02.1 | And today we're not going to worry about deep questions about whether or not that information |
| 1:07.1 | processing is sufficient for consciousness or anything like that. |
| 1:10.5 | We're going to get our |
| 1:11.6 | hands dirty a little bit and think about the connection between what goes on in our brains, |
| 1:17.4 | our nervous systems, and our bodies. There's a constant interaction. In fact, it's even, of course, |
| 1:23.5 | a little bit of a mistake to separate our brains from our bodies because our brains |
| 1:28.2 | are part of our bodies. So in reality, we're going to be talking about interactions between |
| 1:33.1 | two different parts of our bodies, how we move around in the world, and how our brains send |
| 1:39.7 | signals back and forth, receiving signals and then transmitting them to the nervous system, which then does things. |
| 1:46.2 | We've also talked recently on the podcast about the connectome, the idea that if you knew every neuron in a brain, |
| 1:54.1 | or maybe some coarse-grained version of groups of neurons, and how they connected to each other, |
| 2:00.2 | you would have the wiring diagram |
| 2:01.6 | of the brain. And so we have some wiring diagrams for simple organisms, nowhere close to human |
| 2:07.7 | beings yet, but we're working on that. What does that give us, knowing the wiring diagram, |
| 2:12.9 | knowing how that information flows around? How does that then go into controlling our bodies and what we do and our behavior? |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Sean Carroll, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Sean Carroll and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright Ā© Tapesearch 2026.

