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Danny Jones Podcast

#344 - Top Chemist Just Discovered How to Hack the Brains Internal DMT Molecule | Chris McCurdy

Danny Jones Podcast

Danny Jones

Society & Culture, Documentary, Comedy

4.4777 Ratings

🗓️ 27 October 2025

⏱️ 160 minutes

🧾️ Download transcript

Summary

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Chris McCurdy is a pharmaceutical scientist and pharmacist whose research focuses on the design, synthesis and development of drugs to treat pain and drug abuse. His latest research investigates a naturally occurring molecule that may regulate an enzyme which helps produce the powerful psychedelic compound dimethyltryptamine, or DMT, in the body. SPONSORS https://expressvpn.com/dannyjones - Get up to 4 extra months free. https://mnniceethno.com/dj - Use code DJ22 for 22% off your first order. https://ver.so/danny - Use code DANNY for 15% off your order. https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off EPISODE LINKS https://pharmacy.ufl.edu/profile/mccurdy-christopher https://pubmed.ncbi.nlm.nih.gov/?term=McCurdy+CR&cauthor_id=33213215 FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - The most hallucinogenic plant in existence 09:39 - Natural DMT in our bodies & schizophrenia 19:43 - Finding DMT in spinal fluid 27:06 - Endogenous tripping & transcendental meditation 37:26 - Placebo effect & treating cancer with the brain 47:08 - The flaw in the "healthcare equation" 57:18 - Why coca leaves should be legal 01:13:44 - Only 3 countries where coca leaves are legal 01:17:18 - Kratom's dangerous trajectory 01:29:15 - World's biggest kratom study 01:43:01 - 7 hydroxy products (7-OH) vs. kratom 01:47:12 - The drug with the deadliest withdrawal process 01:59:52 - Why ritalin shouldn't be prescribed to kids 02:07:46 - How Modafinil works 02:14:55 - The kanna plant 02:20:02 - FDA finds how much kratom leads to overdose 02:28:12 - Different strains of kratom leaf Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0

Ayo here. We know Christmas hosting can be a headache. Too many dishes, not enough oven space,

0:06.3

and a kettle that's struggling to keep up. This year, swap chaos for calm. We've got dishwashers

0:11.9

to tackle the washing up, range cookers that'll fit a feast and hot taps to keep the bruise

0:16.8

flowing. And with delivery, installation and finance options available, you can get sorted early.

0:22.5

So when your house fills up, you're free to enjoy it. Shop now at a.com.

0:27.2

Hey, oh, let's go. Sean has had some good ideas over the years, but using Canva was a really good one.

0:38.6

Sean designed some social posts to promote his friend's car boot sale.

0:43.7

They looked good.

0:45.9

Really, really good.

0:48.2

Next thing he knows, someone came and bought the lot, including the car.

0:56.8

Now Sean doesn't know how he's going to get home.

0:59.3

Thanks, Canva.

1:11.5

I learned about you through Andrew Gallimore, who was on here.

1:23.0

And him and Nautics were working together on a project they wanted you to get involved with to figure out this endogenous DMT production stuff.

1:25.6

I want to start by talking about that stuff.

1:30.7

But before that, can you give people like a brief history of yourself, your background,

1:31.9

and your work and your expertise?

1:32.8

Sure, sure.

1:35.4

So thanks, first of all, for having me down here. And this is pretty cool.

1:37.0

And it's nice to do this on a local trip too.

1:40.0

Yes.

1:40.5

Because I come just from Gainesville, about two and a half hours up the road.

...

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