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The Curbsiders Internal Medicine Podcast

#342 Checkpoint Inhibitors: The power, and adverse effects, of immunotherapy (ACP 2022)

The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.83.1K Ratings

🗓️ 27 June 2022

⏱️ 55 minutes

🧾️ Download transcript

Summary

With great power comes great immunogenicity. Learn about the ins and outs of immunotherapy–its indications, its power, and its adverse effects–in this episode with Dr. Christian Cable, hematologist/oncologist and medical educator extraordinaire. We learn a riveting history of immunotherapy and about how checkpoint inhibitors work, as well as the best practices for identifying downstream effects of checkpoint inhibitors and their immune system activation (it’s all about the -Itis!).

Claim free CME for this episode at curbsiders.vcuhealth.org!


Show Segments

  • Intro
  • What is Immunotherapy?
  • A History Lesson
  • Immune Checkpoint Inhibitors (ICIs)
  • Immune Related Adverse Events (irAEs)
  • Endocrine complications of checkpoint inhibitors
  • Rheumatologic complications of checkpoint inhibitors
  • Considerations before starting checkpoint inhibitors (and what labs to check)
  • Diagnosing and Managing irAEs
  • Common post-irAE questions
  • New Kids on the Block: CAR-T
  • Take Home Points

Credits

  • Written and Produced by: Nora Taranto MD
  • Hosted by: Molly Heublein MD; Nora Taranto MD; Paul Williams MD, FACP
  • Guests: Christian Cable MD
  • Show Notes: Nora Taranto MD
  • Cover Art: Andrea Perdigão
  • Infographics: Andrea Perdigão
  • Reviewer: Emi Okamoto MD, FACP
  • Production team: Pod Paste
Learn more or apply at scpmgphysiciancareers.com

Sponsor: Locumstory
Visit locumstory.com to learn more about locums.

Full transcript HERE

The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit

Transcript

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0:00.0

Hey, curbsiders! This is Dr. Carolyn Chan, and I'm excited to announce a new mini-series

0:05.6

the Curbsiders Addiction Medicine. We have 11 great episodes for you where we cover core

0:10.8

addiction med topics tailored to the general internist, and we will be releasing these weekly

0:15.6

episodes starting in July. I'll be joined by my co-host, Dr. Sean Cohen, Dr. Kenny Mour for

0:20.7

an Ann, Dr. Natalie Stahl. We believe it's important as ever for internists to play a key

0:25.6

role in providing evidence-based addiction treatment. So be sure to tune in this summer wherever

0:30.8

you listen to podcasts. You can learn more by checking out our website at thecurbsiders.com

0:35.8

or email us at curbsidersaddictionmed at gmail.com.

0:44.8

The Curbsiders Podcast is for entertainment, education, and information purposes only,

0:47.6

and the topics discussed should not be used solely at Diagnostreat, your or prevent any disease

0:50.4

or conditions. For more of the views and statements expressed on this podcast are solely those

0:52.8

of those and should not be interpreted to reflect official policy or position of any entity

0:55.2

besides run possible, cash like more hospital and affiliate outreach programs. If indeed there

0:58.0

are any, in fact, there are none. Pretty much we are responsible if you screw up. You should

1:00.6

always be your own home or endless no-one wrong.

1:10.4

This is Paul Williams. I am here at ACP 2022 with my excellent colleagues, Dr. Norot Toronto,

1:15.9

Dr. Mali Hoidline, and Dr. Chris The Tumayan Choo, who is off-mic. We had an excellent episode.

1:22.1

Eduardo is elsewhere, the less said the better, but we're going to muddle through without him.

1:26.9

But on tonight's show, we have the pleasure of talking to Dr. Christian Cable about

1:31.7

these immune checkpoint inhibitors and their role in medicine and the potential things that

1:36.0

can go wrong with them. And we'll talk more about that in a bit. But before we do that,

1:40.5

I'm going to completely throw her off and ask Norot to tell us what exactly it is that we do here.

...

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