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The Peter Attia Drive

#330 – Autism, ADHD, and Anxiety: Understanding the rise in autism and a multidisciplinary approach to diagnosis and treatment of each condition in children | Trenna Sutcliffe, M.D.

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.77.3K Ratings

🗓️ 6 January 2025

⏱️ 117 minutes

🧾️ Download transcript

Summary

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Trenna Sutcliffe is a developmental behavioral pediatrician and the founder and medical director of the Sutcliffe Clinic in the San Francisco Bay Area, where she partners with families to provide care for children facing behavioral challenges, developmental differences, and school struggles. In this episode, Trenna shares her journey into developmental and behavioral pediatrics, including her pioneering work at Stanford and her expertise in autism, ADHD, and anxiety—the "three As." She explores the diagnostic processes, the overlap and comorbidities of these conditions, and the importance of personalized treatment plans that address both medical and environmental factors. Trenna offers valuable insights into the changing prevalence of autism, the impact of evolving diagnostic criteria, and the range of therapies and medications available to support children and their families. She also discusses the challenges in accessing care and the critical need for a holistic approach that bridges healthcare and education.

We discuss:

  • Trenna’s passion for developmental-behavioral pediatrics (DBP), and the process of diagnosing anxiety, ADHD, and autism [3:15];
  • Understanding anxiety and ADHD: assessing impairment and self-esteem and identifying anxiety and emotional well-being in young patients [9:45];
  • The evolving diagnosis of autism: understanding the spectrum and individual needs [16:30];
  • The dramatic rise in autism spectrum disorder (ASD): genetics, environment, expanded diagnostic criteria, and more [25:45];
  • Exploring epigenetics and the potential multigenerational impact of environment exposures on susceptibility to certain disorders [37:15];
  • The evolution of autism classifications, and the particular challenges for children with level 1 (mild) autism due to a lack of support [41:15];
  • The broadening of the autism spectrum: benefits and risks of expanded diagnostic criteria and the need for future frameworks to focus on better outcomes [48:00];
  • The overlap between ASD, ADHD, and anxiety [57:15];
  • Understanding oppositional defiant disorder, and the importance of understanding the “why” behind a behavior when creating treatment plans [1:00:45];
  • Defining developmental-behavioral pediatrics (DBP), and Trenna’s professional journey [1:07:00];
  • Updated methods of ABA (applied behavioral analysis) therapy: evolution, controversies, challenges of scaling autism care, and the need for tailored interventions [1:13:45];
  • Advice for parents trying to find and evaluate care for children with autism, ADHD, or anxiety [1:22:45];
  • Tailored treatments for ADHD: balancing stimulant medications with behavioral training [1:28:30];
  • The interplay between medication, behavioral therapy, and neuroplasticity in managing ADHD, and the potential to grow out of the need for medication [1:39:45];
  • Using medication to treat anxiety and other symptoms in kids with autism without ADHD [1:44:45];
  • FAQs about medicating children with ADHD: benefits, side effects, dosage, and more [1:46:30];
  • The “superpowers” associated with level 1 autism [1:48:45];
  • The next steps to increase support for children with ASD, anxiety, and ADHD [1:50:45]; and
  • More.

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Transcript

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0:00.0

Hey everyone. Welcome to the Drive podcast. I'm your host, Peter Attia. This podcast, my website, and my weekly newsletter all focus on the goal of translating the science of longevity

0:21.5

into something accessible for everyone. Our goal is to provide the best content in health and

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wellness, and we've established a great team of analysts to make this happen. It is extremely

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our work is made entirely possible

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by our members, and in return, we offer exclusive member-only content and benefits above and beyond

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it's our goal to ensure members get back much more than the price of the subscription. If you want to

0:55.0

learn more about the benefits of our premium membership, head over to peteratia m.com forward slash

1:01.6

subscribe. My guest this week is Dr. Trenna Sutcliffe. Trenna is a developmental, behavioral

1:09.4

pediatrician and the founder and medical director of the Sutcliffe Clinic inrenna is a developmental, behavioral pediatrician and the founder and medical director

1:12.1

of the Sutcliffe Clinic in the Bay Area, which partners with patients and their families to

1:16.7

evaluate and provide supportive care for children dealing with issues such as behavioral changes,

1:21.5

developmental differences, and school struggles. In my conversation with Trenna, we explore her journey

1:26.3

into developmental and behavioral

1:28.0

pediatrics. In fact, she was the first person to be practicing under this designation

1:33.8

at Stanford when she arrived about 20 years ago. This includes her background in genetics,

1:38.5

pediatric neurology, and her current work in leading multidisciplinary teams around the care

1:43.6

of children with autism, ADHD,

1:45.3

and anxiety. We spoke about the diagnostic processes for autism, ADHD, and anxiety, which

1:50.7

calls the 3A's, discussing how these behavioral diagnoses are made based on clinical traits

1:55.2

and the criteria depending on the age of a child. We focus on the overlap between the three A's

...

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