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Nature Podcast

30 April 2020: A sniff test for consciousness, and how to cut antibiotics use — with vaccines

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 29 April 2020

⏱️ 23 minutes

🧾️ Download transcript

Summary

This week, how the ‘sniff-response’ can help clinicians determine a patient's state of consciousness, and how vaccines could help drive down antibiotic use.


In this episode:


00:45 Sniffing out consciousness

Researchers have found that the sniff reflex can indicate whether a patient is in a vegetative state, and even the likelihood that they will recover consciousness. Research Article: Arzi et al.


08:37 Research Highlights

The stupefying effect of carbon dioxide, and a chameleon gemstone that tricks your eyes. Research Highlight: Rising carbon dioxide levels will make us stupiderResearch Highlight: How a chameleon gemstone changes from red to green


11:12 Vaccination and antibiotic usage

Looking at data from low- and middle-income countries, researchers have determined that vaccination could prevent millions of infections currently treated by antibiotics. Research Article: Lewnard et al.


16:49 Pick of the Briefing

We pick our highlights from the Nature Briefing, including the forgotten mother of climate change science, and a new global study on insect declines. Chemistry World: Eunice Foote: the mother of climate changeScience: Meta-analysis reveals declines in terrestrial but increases in freshwater insect abundances

Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.


Other links

Shamini’s latest video on a newly discovered Spinosaurus skeleton, which suggests that it had a fin-like tail that would have helped it swim and hunt.


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Transcript

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0:00.0

nature an experiment i really know yet why is like so far like it sounds so simple they had no idea

0:10.7

but now the data's i find this not only refreshing but but at some level astounding nature

0:20.4

welcome back to the Nature.

0:25.6

Welcome back to the nature podcast.

0:29.2

This week, what a sniff reveals about consciousness and the relationship between vaccines and antibiotic use.

0:33.5

I'm Charmany Bandelle.

0:34.7

And I'm Nick Howe.

0:45.8

Yeah. I'm Charmany Bandelle. And I'm Nick Howe. Imagine you're walking in a park.

0:49.1

It's a beautiful sunny day with flowers everywhere.

0:52.4

And what a lovely smell.

0:57.4

Now, I'm not just trying to keep you sane during lockdown. Humans often inhale through

1:03.1

their nose when they smell something nice. It's an automatic response. Now researchers think

1:08.9

that this sniff reflex could help doctors assess an immobile patient's level

1:13.5

of consciousness. That's according to a new study in this week's nature. I called up one of the

1:18.7

authors, Anath Arzi, to find out more, and she started by telling me about different levels

1:23.9

of consciousness. In particular, the difference between a vegetative and a minimally

1:29.0

conscious state.

1:30.3

A person that is diagnosed in vegetative state is someone that has a sleep-wake cycle

1:38.3

and the eyes are spontaneously open. However, we have no evidence for any signs of conscious awareness for the self

1:48.2

or to the environment. So we have no ability to communicate with this person and this person

1:54.0

has no ability to communicate. For minimally conscious patients, they have a severe altered consciousness. However, there are

2:03.8

subtle signs of consciousness. We have evidence that this person has some awareness of the

...

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